{"id":"W2288165580","doi":"10.1371/journal.pone.0148640","title":"Lipid Droplet Formation, Their Localization and Dynamics during Leishmania major Macrophage Infection","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Lipid metabolism and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Agence Nationale de la Recherche; Canadian Institutes of Health Research; L'Oreal USA","keywords":"Leishmania; Biology; Macrophage; Cell biology; Intracellular parasite; Parasite hosting; Cytoplasm; Lipid droplet; Vacuole; Obligate parasite; Obligate; Leishmania major; Intracellular; Host (biology); Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007730013,0.0001022859,0.0001025584,0.00003772562,0.0001077967,0.00002339295,0.00005158735,0.0001003687,0.00002205019],"category_scores_gemma":[0.0000621053,0.0000714597,0.0000243346,0.00004961106,0.00003661533,0.00001705302,0.00006398968,0.00002581077,0.00001670307],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001693869,"about_ca_system_score_gemma":0.00001081039,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007645895,"about_ca_topic_score_gemma":0.00007645535,"domain_scores_codex":[0.9994235,0.00003315393,0.0001422999,0.0001778434,0.00008490336,0.0001382999],"domain_scores_gemma":[0.9996405,0.000006482484,0.00006316807,0.0001722075,0.00006820093,0.0000494249],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003278012,0.0001336213,0.01236277,0.00008771892,0.00005288491,2.508935e-7,0.00002997115,4.803517e-7,0.9825992,0.00003496844,0.00004032314,0.004625024],"study_design_scores_gemma":[0.0004017523,0.00004172977,0.01343323,0.00005135588,0.00003641451,0.000003821707,0.00000971609,0.0002204005,0.9839478,0.00001737766,0.001710726,0.000125684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931111,0.0001267299,0.006266796,0.0001232808,0.00004441509,0.0001250564,0.00002878785,0.00002565711,0.0001481357],"genre_scores_gemma":[0.9979144,0.00072061,0.0002576745,0.00005915959,0.0003643901,0.00001429289,0.00006922014,0.00001662396,0.0005835759],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006009122,"threshold_uncertainty_score":0.2914042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008920983046138687,"score_gpt":0.1794689410448458,"score_spread":0.1705479579987071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}