{"id":"W2288223969","doi":"10.1038/srep22129","title":"Engineering Dark Chromoprotein Reporters for Photoacoustic Microscopy and FRET Imaging","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Photoacoustic and Ultrasonic Imaging","field":"Engineering","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Terry Fox Foundation; Cancer Research Institute","keywords":"Förster resonance energy transfer; Fluorescence; Biosensor; Photoacoustic imaging in biomedicine; Microscopy; Biophysics; Chromophore; Chemistry; Biology; Biochemistry; Optics; Photochemistry; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009234016,0.0002356024,0.0002347838,0.0001784163,0.0001857195,0.0002401416,0.0001028136,0.00004839688,0.00003277946],"category_scores_gemma":[0.0002754979,0.0001910271,0.00007697976,0.0001882043,0.0001398611,0.0002959852,0.00003665105,0.00008500767,0.000005154122],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001176248,"about_ca_system_score_gemma":0.00006111046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008156896,"about_ca_topic_score_gemma":0.000001478635,"domain_scores_codex":[0.9980313,0.000006038061,0.0004950499,0.0006606927,0.0002374742,0.0005694013],"domain_scores_gemma":[0.9989496,0.00008510343,0.0001065668,0.000612625,0.00007871894,0.0001673248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000002500184,0.000006622564,0.0007233415,0.0001180159,0.00002063885,0.0002056611,0.0001075542,0.0004401907,0.9857478,0.000005700178,0.009099412,0.003522601],"study_design_scores_gemma":[0.0007714431,0.00002114875,0.0009298098,0.0007555345,0.000119513,0.003354397,0.0001627006,0.0919588,0.8682625,0.003482983,0.02910314,0.001078074],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6369426,0.0006558681,0.3509304,0.0001055115,0.009396619,0.0007693552,0.00002909115,0.0006787761,0.0004917966],"genre_scores_gemma":[0.9921638,0.000009126281,0.00686004,0.00001683704,0.00009436635,0.0001020502,0.00001267338,0.00006281034,0.0006782663],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3552212,"threshold_uncertainty_score":0.7789859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004210711158154972,"score_gpt":0.1995308051954829,"score_spread":0.1953200940373279,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}