{"id":"W2288223969","doi":"10.1038/srep22129","title":"Engineering Dark Chromoprotein Reporters for Photoacoustic Microscopy and FRET Imaging","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Photoacoustic and Ultrasonic Imaging","field":"Engineering","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Terry Fox Foundation; Cancer Research Institute","keywords":"Förster resonance energy transfer; Fluorescence; Biosensor; Photoacoustic imaging in biomedicine; Microscopy; Biophysics; Chromophore; Chemistry; Biology; Biochemistry; Optics; Photochemistry; Physics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001141136,0.0006805521,0.0005536524,0.0004563035,0.0002678769,0.0007344882,0.001153975,0.0007576863,0.0007679716],"category_scores_gemma":[0.0009814505,0.0005111322,0.000496625,0.0005999254,0.0006313942,0.0006224416,0.0008283589,0.001719248,0.0007481217],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007392943,"about_ca_system_score_gemma":0.0004503688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007007265,"about_ca_topic_score_gemma":0.001098655,"domain_scores_codex":[0.9993936,0.0001327916,0.00006110894,0.0001083128,0.0002146266,0.0000894447],"domain_scores_gemma":[0.9994308,0.0001678453,0.0001268115,0.0001040003,0.00009174939,0.00007873401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003928888,0.00003354766,0.00007648892,0.00001820443,0.000003846524,0.00003887531,0.00002362386,0.0003062864,0.9973127,0.0005156124,0.00003256591,0.001598957],"study_design_scores_gemma":[0.000008051153,0.00004879493,0.0001677852,0.000002386271,0.000004877709,0.00006976179,0.00001277735,0.002833113,0.9953769,0.00008860201,0.001380554,0.000006394609],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6857956,0.0007091376,0.30835,0.0003608232,0.00008333432,0.0004853085,0.0006913269,0.0009653357,0.002559106],"genre_scores_gemma":[0.7609897,0.0008688833,0.2305135,0.0001281574,0.00001223759,0.0004620574,0.001584777,0.0004771916,0.004963518],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001153975,"threshold_uncertainty_score":0.00603497,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004210711158154972,"score_gpt":0.1995308051954829,"score_spread":0.1953200940373279,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}