{"id":"W2288267488","doi":"10.4049/jimmunol.1502198","title":"CD44 Antibody Inhibition of Macrophage Phagocytosis Targets Fcγ Receptor– and Complement Receptor 3–Dependent Mechanisms","year":2016,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; McMaster University; Canadian Blood Services; St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Phagocytosis; Receptor; Macrophage; Complement receptor; Antibody; Fc receptor; Complement (music); Chemistry; Cell biology; Immunology; Biology; Complement system; Biochemistry; Gene; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002123507,0.000455556,0.0003752717,0.0002360221,0.0001656174,0.0002335007,0.0002642928,0.0004134511,0.001092313],"category_scores_gemma":[0.0001194886,0.0001149736,0.0004818263,0.0001105049,0.0001895379,0.0001794113,0.0002005468,0.0008370883,0.0002501572],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003485331,"about_ca_system_score_gemma":0.0003714577,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006493265,"about_ca_topic_score_gemma":0.0008304802,"domain_scores_codex":[0.9996768,0.00005322931,0.00002442071,0.00002583297,0.00009245603,0.0001271897],"domain_scores_gemma":[0.9999068,0.00001777222,0.00002436135,0.00001254536,0.00002137552,0.00001726367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001511249,0.0001081804,0.0001779871,0.00007756425,0.00001380952,0.00004385921,0.00001118483,0.00006745289,0.9965396,0.0001666133,0.00005912273,0.002583547],"study_design_scores_gemma":[0.00002818784,0.0008092068,0.004107358,0.00000878629,0.0000245441,0.0002154106,0.00001201688,0.0008317506,0.9923096,0.00004969121,0.001600192,0.000003410597],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916755,0.003404514,0.002242704,0.0001624195,0.00004155523,0.00004855057,0.00007787224,0.00005111293,0.002295648],"genre_scores_gemma":[0.993468,0.001911692,0.001892328,0.0001115623,0.00002536603,0.00006006443,0.0001946838,0.000007334106,0.00232908],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001092313,"threshold_uncertainty_score":0.003654182,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01240517248454629,"score_gpt":0.2491333760915913,"score_spread":0.236728203607045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}