{"id":"W2288355178","doi":"10.3390/v8020045","title":"Big Data Offers Novel Insights for Oncolytic Virus Immunotherapy","year":2016,"lang":"en","type":"review","venue":"Viruses","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Children's Hospital of Eastern Ontario","funders":"Terry Fox Research Institute; Canada Foundation for Innovation; Ontario Institute for Cancer Research","keywords":"Oncolytic virus; Immunotherapy; Virus; Computational biology; Virology; Biology; Data science; Medicine; Computer science; Immunology; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003340874,0.001347983,0.001754196,0.002968138,0.0006030006,0.003799558,0.001578108,0.00373896,0.005427335],"category_scores_gemma":[0.003907735,0.0005150228,0.001401107,0.003121625,0.002413324,0.007314814,0.002317204,0.006629967,0.00234097],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002414538,"about_ca_system_score_gemma":0.003177115,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00124598,"about_ca_topic_score_gemma":0.00200683,"domain_scores_codex":[0.9990789,0.0002851598,0.00009073183,0.000145845,0.0003274463,0.00007191916],"domain_scores_gemma":[0.9966105,0.002371877,0.0001888455,0.0001543139,0.0004533214,0.0002210925],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006521853,0.00006443241,0.0003595189,0.01021003,0.0002658569,0.0003198376,0.000224507,0.001111058,0.001609187,0.09320584,0.08635143,0.806213],"study_design_scores_gemma":[0.00001051675,0.00003510502,0.0003014396,0.002794833,0.00005197754,0.000341357,0.0001055271,0.0002319051,0.0003273356,0.03087205,0.9648954,0.00003248421],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001077658,0.9858991,0.001860943,0.007870488,0.001589744,0.00001431904,0.0000694698,0.00003626148,0.002551914],"genre_scores_gemma":[0.00155757,0.9908222,0.001647084,0.002883815,0.001629182,0.00002922762,0.00008862506,0.00001333452,0.001328965],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005427335,"threshold_uncertainty_score":0.01815623,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2208431477668568,"score_gpt":0.4201771659172877,"score_spread":0.1993340181504309,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}