{"id":"W2288737088","doi":"10.1182/blood.v122.21.2682.2682","title":"An Update On The Robust Clinical Activity Of SL-401, a Targeted Therapy Directed To The Interleukin-3 Receptor On Cancer Stem Cells and Tumor Bulk, In Patients With Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)","year":2013,"lang":"en","type":"article","venue":"Blood","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Interleukin-3 receptor; Medicine; Plasmacytoid dendritic cell; Cancer; Myeloid; Internal medicine; Leukemia; Cancer research; Oncology; Immunology; Immune system; Dendritic cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002550745,0.0002759625,0.0003901642,0.00008418086,0.0001487725,0.00003469506,0.0003752272,0.0001538559,0.0004131534],"category_scores_gemma":[0.00002905813,0.0001470138,0.00005970363,0.0001772802,0.0001788799,0.000086254,0.00006704395,0.0005496308,0.0001826322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002766233,"about_ca_system_score_gemma":0.00006259237,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002714819,"about_ca_topic_score_gemma":0.0002447037,"domain_scores_codex":[0.9981164,0.0006287014,0.0003637972,0.0004313632,0.00008022841,0.0003794798],"domain_scores_gemma":[0.9987069,0.0004639009,0.0002027034,0.0004906792,0.00008885011,0.00004698928],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003889355,0.006402235,0.01862682,0.00002576652,0.0004204804,0.000003587987,0.001214707,0.0002408116,0.9583892,0.00007900024,0.001187617,0.009520467],"study_design_scores_gemma":[0.0068052,0.004524961,0.1286647,0.0001426928,0.00004942067,0.000001896616,0.0001944187,0.00005329068,0.8581908,0.000007962156,0.001086311,0.0002783316],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976545,0.0001471662,0.00001155317,0.0002426125,0.0005385437,0.001194144,0.0001443668,0.00003886546,0.0000282362],"genre_scores_gemma":[0.9989155,0.0001093999,0.00007330145,0.0005077537,0.00002440103,0.0001778693,0.00001373667,0.00003494096,0.0001430913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1100379,"threshold_uncertainty_score":0.5995046,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01088312130951458,"score_gpt":0.2161166961144984,"score_spread":0.2052335748049839,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}