{"id":"W2288839105","doi":"10.1016/j.expneurol.2016.03.001","title":"Loss of Ca2+-permeable AMPA receptors in synapses of tonic firing substantia gelatinosa neurons in the chronic constriction injury model of neuropathic pain","year":2016,"lang":"en","type":"article","venue":"Experimental Neurology","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Neuroscience; AMPA receptor; Glutamatergic; Inhibitory postsynaptic potential; Neuropathic pain; Excitatory postsynaptic potential; Chemistry; Nerve injury; Neurotransmission; Tonic (physiology); Glutamate receptor; Receptor; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003690365,0.0003917754,0.0007307508,0.0006526128,0.0005681915,0.0005260893,0.0007767107,0.0009213208,0.00161306],"category_scores_gemma":[0.000264446,0.0004143165,0.0005128366,0.0004331545,0.0011,0.0009832259,0.0003927626,0.001729066,0.0002836396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006181876,"about_ca_system_score_gemma":0.0005716294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004833078,"about_ca_topic_score_gemma":0.005406677,"domain_scores_codex":[0.9995566,0.00003960399,0.00003712066,0.00006554751,0.0001256178,0.0001754648],"domain_scores_gemma":[0.9997601,0.00001931514,0.00006286427,0.00003170829,0.0000297538,0.00009624514],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000489578,0.00008160916,0.0001777982,0.00005563489,0.00002089401,0.0001664757,0.00004545128,0.00003764043,0.9980959,0.0001231396,0.00003021025,0.0006755847],"study_design_scores_gemma":[0.0001061489,0.001324045,0.02135986,0.00002098003,0.0001407455,0.001990105,0.0002958979,0.00194124,0.9716311,0.0001684582,0.001003579,0.00001793456],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963831,0.001325476,0.001188646,0.0001536514,0.00003637181,0.00001381351,0.0001271022,0.00003445762,0.0007375456],"genre_scores_gemma":[0.9961437,0.0006053763,0.000845543,0.00003370962,0.000007782675,0.00002945257,0.0001157583,0.0000130632,0.002205551],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004833078,"threshold_uncertainty_score":0.009609878,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01921135262943776,"score_gpt":0.2692047510843984,"score_spread":0.2499933984549606,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}