{"id":"W2290003209","doi":"10.1128/msphere.00080-15","title":"The Zinc Finger Protein Mig1 Regulates Mitochondrial Function and Azole Drug Susceptibility in the Pathogenic Fungus Cryptococcus neoformans","year":2016,"lang":"en","type":"article","venue":"mSphere","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Burroughs Wellcome Fund","keywords":"Cryptococcus neoformans; Biology; Mitochondrion; Saccharomyces cerevisiae; Microbiology; Antifungal drug; Cell biology; Genetics; Gene; Candida albicans","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007188364,0.0002624237,0.0001427936,0.0002676428,0.0001513522,0.0002056361,0.0001233128,0.0001737337,0.0005284952],"category_scores_gemma":[0.00009387668,0.00008928606,0.0001261135,0.000118568,0.0001615344,0.0000709601,0.000199166,0.0002292635,0.0001680774],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004523971,"about_ca_system_score_gemma":0.0001655642,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001921394,"about_ca_topic_score_gemma":0.002279076,"domain_scores_codex":[0.9999065,0.000009470494,0.000006135686,0.00001761681,0.0000245798,0.0000356942],"domain_scores_gemma":[0.9999281,0.000007116092,0.00002613757,0.000004699913,0.00001046618,0.00002342094],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001542558,0.000024949,0.00326683,0.00001616592,0.00000437582,0.000136531,0.00001878383,0.0001066295,0.9945314,0.00004349466,0.00005030267,0.001646227],"study_design_scores_gemma":[0.00003204938,0.0002674507,0.3330552,0.00001398138,0.00003830296,0.001051294,0.0002097086,0.005015763,0.6577675,0.0001444993,0.002386506,0.00001770975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983973,0.0004898087,0.0003906289,0.00004157931,0.000004733249,0.000007036075,0.0001699277,0.00004132174,0.0004576672],"genre_scores_gemma":[0.9987122,0.0001513642,0.000251724,0.00002278099,0.000001770591,0.000006239307,0.0001329283,0.000004735428,0.000716191],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001921394,"threshold_uncertainty_score":0.003820479,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009019558515006458,"score_gpt":0.2287840070364029,"score_spread":0.2197644485213965,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}