{"id":"W2290120390","doi":"10.1111/xen.12225","title":"First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes – Chapter 3: Porcine islet product manufacturing and release testing criteria","year":2016,"lang":"en","type":"article","venue":"Xenotransplantation","topic":"Xenotransplantation and immune response","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Xenotransplantation; Islet; Medicine; Statement (logic); Diabetes mellitus; Product (mathematics); Internal medicine; Transplantation; Endocrinology; Political science; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.07220178,0.001692038,0.003539352,0.005612218,0.00256,0.008635805,0.009072996,0.02136584,0.0130486],"category_scores_gemma":[0.07850412,0.00150833,0.004891634,0.004425335,0.003030887,0.004295209,0.005664067,0.015275,0.01823217],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005574718,"about_ca_system_score_gemma":0.03803251,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01353158,"about_ca_topic_score_gemma":0.02022075,"domain_scores_codex":[0.9550442,0.01100995,0.01098944,0.001519877,0.01884159,0.002594899],"domain_scores_gemma":[0.8860364,0.03087589,0.01088174,0.003713632,0.06053368,0.007958641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001207484,0.0002335472,0.0007779687,0.001889457,0.00004081641,0.0003777171,0.0002320238,0.0003214744,0.001246823,0.005632114,0.9204386,0.0686886],"study_design_scores_gemma":[0.0001074262,0.0001240348,0.00302477,0.005270181,0.00005570397,0.000575438,0.0001776125,0.0001368609,0.0005403385,0.002964809,0.9869469,0.00007581608],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"methods","genre_scores_codex":[0.003761893,0.143357,0.0380351,0.4521459,0.1110102,0.01106145,0.02257962,0.002222493,0.2158264],"genre_scores_gemma":[0.01352904,0.1263817,0.1072436,0.5274633,0.03845631,0.02089528,0.04626971,0.001745435,0.1180156],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.07220178,"threshold_uncertainty_score":0.3818441,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1206787382242195,"score_gpt":0.3875939756575952,"score_spread":0.2669152374333758,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}