{"id":"W2290159696","doi":"10.1016/j.jalz.2015.08.144","title":"P4‐314: Epitope‐specific amyloid‐β oligomer vaccination ameliorates amygdala‐dependent memory deficits and inhibits region‐to‐region spread of plaque pathology in APP/PS1 mice","year":2015,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Emergent BioSolutions (Canada); University of British Columbia","funders":"","keywords":"Immunology; Epitope; Titer; Analysis of variance; Medicine; Internal medicine; Psychology; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001796994,0.0006941797,0.0006216292,0.0005374948,0.0001937132,0.0002697704,0.0004664637,0.0005872874,0.002001077],"category_scores_gemma":[0.000176991,0.0002164642,0.0003082188,0.0001728439,0.0004305331,0.0003780248,0.000208082,0.001029408,0.001006208],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002605392,"about_ca_system_score_gemma":0.0002793926,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005085454,"about_ca_topic_score_gemma":0.0005038226,"domain_scores_codex":[0.9998492,0.0000189794,0.00001350312,0.00003383379,0.00003137347,0.00005315696],"domain_scores_gemma":[0.9998232,0.00001238255,0.00006605509,0.00001839478,0.00001778135,0.00006228542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001627845,0.0007269311,0.0002169466,0.00007158809,0.0000134429,0.0001222929,0.00002957563,0.0001527064,0.9935592,0.00006413541,0.0001704361,0.003244901],"study_design_scores_gemma":[0.000605,0.01508463,0.01377598,0.00004885565,0.00008385231,0.001091063,0.0001079191,0.00203039,0.9627369,0.0004024844,0.004002328,0.00003043203],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970925,0.0003872227,0.000779764,0.0001330257,0.00004005615,0.00003871085,0.0004449315,0.0001774806,0.000906377],"genre_scores_gemma":[0.9901246,0.0006193556,0.001637348,0.0001194863,0.00003803316,0.0001165342,0.0008506586,0.00006259621,0.006431475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002001077,"threshold_uncertainty_score":0.006694257,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04652658802745703,"score_gpt":0.2983557144814087,"score_spread":0.2518291264539517,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}