{"id":"W2290369451","doi":"10.1096/fasebj.23.1_supplement.492.3","title":"The CrkRS/CDK12 kinase is activated by a novel isoform of Cyclin K and phosphorylates the C‐terminal domain of RNA Pol II","year":2009,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria; BC Cancer Agency","funders":"","keywords":"Cyclin D; Cyclin-dependent kinase complex; Cyclin A; Cyclin A2; Cyclin-dependent kinase; Cyclin; Molecular biology; Cyclin-dependent kinase 9; Cyclin B; Cell biology; Cyclin E; Biology; Chemistry; Cyclin-dependent kinase 2; Kinase; Biochemistry; Cell cycle; Protein kinase A; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006522062,0.000448704,0.0002181613,0.0002444551,0.0002556111,0.0003942686,0.0002597304,0.0001898296,0.001124938],"category_scores_gemma":[0.0001134337,0.0002142243,0.0003065209,0.0001527906,0.0002432298,0.0002184498,0.0001524938,0.0002983152,0.0005610152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006118013,"about_ca_system_score_gemma":0.0002423934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001053483,"about_ca_topic_score_gemma":0.001415294,"domain_scores_codex":[0.9998945,0.000007283802,0.000007333652,0.00004198156,0.00002033961,0.00002842433],"domain_scores_gemma":[0.9999138,0.000006225844,0.00002853006,0.000009188704,0.00001167081,0.00003063194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002264856,0.00001394452,0.0006644813,0.00004357165,0.000005628714,0.0001531658,0.000008460375,0.0000468215,0.9971295,0.0001548797,0.00006149753,0.001491668],"study_design_scores_gemma":[0.00004889617,0.000168068,0.02544937,0.000007592165,0.00002181947,0.001969586,0.0000362834,0.001960486,0.9628326,0.0001044724,0.007388463,0.00001237629],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903866,0.002513386,0.004086465,0.0001224724,0.00005706032,0.00002852133,0.0005432664,0.0001314095,0.002130898],"genre_scores_gemma":[0.9906977,0.0009670334,0.003204054,0.00004011148,0.00002634608,0.00002491394,0.001000536,0.00002616803,0.004013215],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001124938,"threshold_uncertainty_score":0.004438937,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007868974643419985,"score_gpt":0.2572336135093573,"score_spread":0.2493646388659373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}