{"id":"W2290830228","doi":"10.1095/biolreprod.115.133496","title":"Plasminogen Improves Mouse IVF by Interactions with Inner Acrosomal Membrane-Bound MMP2 and SAMP141","year":2016,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Plasmin; Zona pellucida; Cumulus oophorus; Biology; Andrology; Human fertilization; Sperm; Plasminogen activator; Oocyte; Capacitation; Acrosome reaction; Cell biology; Endocrinology; Anatomy; Biochemistry; Embryo; Genetics; Enzyme; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000414296,0.0004828695,0.0004258476,0.0004237393,0.0002122584,0.0004638274,0.000420569,0.0004519271,0.0022735],"category_scores_gemma":[0.0003133051,0.0002106738,0.0004090633,0.0001752252,0.0003038655,0.0003056378,0.0002485616,0.0008936279,0.0004680101],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002316654,"about_ca_system_score_gemma":0.0003014682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008100707,"about_ca_topic_score_gemma":0.001238998,"domain_scores_codex":[0.9996544,0.00008528393,0.00004354257,0.00005789926,0.00007947927,0.0000793705],"domain_scores_gemma":[0.9998084,0.00003610989,0.00005370351,0.00002487889,0.00001893802,0.00005794552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005218148,0.0001354377,0.0002322699,0.00004989763,0.000012965,0.00004271196,0.0000220213,0.00007529921,0.996142,0.00009326632,0.00009750978,0.002574866],"study_design_scores_gemma":[0.00005351976,0.001158685,0.003211242,0.00001115156,0.00003934087,0.0001236142,0.00002776192,0.0005473667,0.9906759,0.00005466014,0.004090792,0.000005986082],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984825,0.006086556,0.004892544,0.0005535367,0.0001200352,0.0001088394,0.0005637006,0.0002701084,0.002579721],"genre_scores_gemma":[0.9848792,0.002431142,0.004784709,0.0001072286,0.00003648027,0.0001082509,0.0006101286,0.00005224531,0.006990592],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0022735,"threshold_uncertainty_score":0.007605612,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01266820762588405,"score_gpt":0.2509109568915684,"score_spread":0.2382427492656844,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}