{"id":"W2290939467","doi":"","title":"Assessing the plasma pharmacokinetics, tissue distribution, excretion and effects on cholesterol pharmacokinetics of a novel hydrophilic compound, FM-VP4, following administration to rats.","year":2002,"lang":"en","type":"article","venue":"PubMed","topic":"Phytochemical Studies and Bioactivities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Pharmacokinetics; Cmax; Cholesterol; Excretion; Oral administration; Pharmacology; Urine; Chemistry; Distribution (mathematics); Endocrinology; Internal medicine; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001517619,0.0005411833,0.0003921122,0.000268383,0.0001505925,0.0002324012,0.0002060056,0.0003543826,0.00122834],"category_scores_gemma":[0.0001744503,0.0001627626,0.0002395856,0.0001438428,0.000304846,0.0004229762,0.0001145566,0.0006913504,0.0003590004],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003590805,"about_ca_system_score_gemma":0.0005514281,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001334973,"about_ca_topic_score_gemma":0.00167629,"domain_scores_codex":[0.999918,0.00001370463,0.000004687055,0.00001988489,0.00002006394,0.0000236957],"domain_scores_gemma":[0.9998417,0.00001917663,0.00005761188,0.0000175764,0.00002499944,0.0000388902],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001658438,0.000236292,0.0006484032,0.00005640448,0.00001490941,0.00006773393,0.00002233258,0.0001088059,0.9915738,0.0000459883,0.00006103084,0.005505864],"study_design_scores_gemma":[0.00008822474,0.01020972,0.005754103,0.000006819083,0.00005888193,0.0002409263,0.00005824669,0.0005712388,0.9812951,0.00004323938,0.001662275,0.00001132552],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969934,0.0008613241,0.001311954,0.00007171157,0.00002299569,0.00003156102,0.0002462922,0.00006198748,0.0003987745],"genre_scores_gemma":[0.9881209,0.001937565,0.003727946,0.00006838105,0.00003053527,0.0001055611,0.0006868703,0.00003291938,0.005289365],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001334973,"threshold_uncertainty_score":0.004109204,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02502027745286157,"score_gpt":0.2802900857408159,"score_spread":0.2552698082879543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}