{"id":"W2291043294","doi":"10.5966/sctm.2015-0288","title":"Strategies and Challenges to Myocardial Replacement Therapy","year":2016,"lang":"en","type":"review","venue":"Stem Cells Translational Medicine","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto","funders":"National Heart, Lung, and Blood Institute; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Regenerative medicine; Cell therapy; Myocardial infarction; Medicine; Transplantation; Stem-cell therapy; Regeneration (biology); Ventricle; Heart failure; Intensive care medicine; Heart transplantation; Heart disease; Stem cell; Neuroscience; Cardiology; Internal medicine; Psychology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002001107,0.0008377571,0.001240408,0.001187028,0.0004407764,0.002151802,0.001359498,0.002653135,0.005150545],"category_scores_gemma":[0.001833502,0.0002201726,0.0005307958,0.0009240761,0.00195063,0.002578453,0.001219545,0.004593415,0.003672546],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008719712,"about_ca_system_score_gemma":0.001564973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005924095,"about_ca_topic_score_gemma":0.0009443109,"domain_scores_codex":[0.9993554,0.0001508202,0.00009039449,0.0001055008,0.000249113,0.00004878236],"domain_scores_gemma":[0.9989348,0.000617019,0.0001051947,0.00003671649,0.0002204053,0.00008592929],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005058407,0.00006732091,0.000137898,0.01252537,0.00005818844,0.0003122243,0.0001689202,0.000437386,0.001341488,0.03426699,0.04183441,0.9087993],"study_design_scores_gemma":[0.000009792828,0.00005937552,0.0002865144,0.00544476,0.0000329448,0.001280815,0.0001650305,0.0001171542,0.0002427031,0.01104195,0.981301,0.00001803831],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006461318,0.9939785,0.0003621951,0.003330756,0.000792819,0.000003279648,0.00000706651,0.000007083709,0.001453737],"genre_scores_gemma":[0.0009012239,0.9948788,0.00055829,0.001546099,0.001269386,0.000009658067,0.00001334334,0.000002570402,0.0008207127],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005150545,"threshold_uncertainty_score":0.01723033,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08684343594109975,"score_gpt":0.3602267100904716,"score_spread":0.2733832741493719,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}