{"id":"W2291374773","doi":"10.4049/jimmunol.182.supp.134.77","title":"Toll-Like Receptor 3 Signaling on Macrophages is Required for Survival Following Coxsackievirus B4 Infection (134.77)","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"TLR3; Coxsackievirus; Innate immune system; Biology; Toll-like receptor; Immunology; Immune system; Signal transduction; Virus; TLR7; miR-155; Adoptive cell transfer; Viral replication; Virology; Enterovirus; Cell biology; microRNA; T cell; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002060037,0.0002761511,0.0001847153,0.0002288172,0.00020855,0.000279118,0.0001402216,0.0003039174,0.001958672],"category_scores_gemma":[0.0001432346,0.0001162778,0.0002442379,0.00008403658,0.0002049874,0.0001581938,0.0003005553,0.0005224272,0.0008023779],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002715359,"about_ca_system_score_gemma":0.0002538302,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005490745,"about_ca_topic_score_gemma":0.0005939552,"domain_scores_codex":[0.9998391,0.00002493288,0.00001257716,0.00001615129,0.0000285289,0.00007875175],"domain_scores_gemma":[0.9998307,0.00001902361,0.00005385622,0.00001899145,0.00002489178,0.00005239769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002883811,0.00002412551,0.0005461487,0.00002513579,0.000002178001,0.00007965925,0.00001377147,0.00001377333,0.9982101,0.00004642829,0.00005814738,0.0006922618],"study_design_scores_gemma":[0.00007886033,0.0007157923,0.06154914,0.00003755571,0.00002833368,0.0007791992,0.0001704777,0.000822199,0.9320678,0.0002009623,0.003540632,0.000009083908],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967086,0.000651322,0.0009368332,0.0001121092,0.00002604661,0.00001692947,0.0004497342,0.00006521935,0.001033107],"genre_scores_gemma":[0.9959564,0.000295067,0.000805362,0.0000675427,0.00000957582,0.00004948651,0.0006531297,0.00001295396,0.002150549],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001958672,"threshold_uncertainty_score":0.006552398,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0224108607291382,"score_gpt":0.2845468437313278,"score_spread":0.2621359830021895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}