{"id":"W2291384654","doi":"10.3390/v8030067","title":"Remodeling of the Host Cell Plasma Membrane by HIV-1 Nef and Vpu: A Strategy to Ensure Viral Fitness and Persistence","year":2016,"lang":"en","type":"review","venue":"Viruses","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Biology; Cell biology; Immune system; Viral replication; Homing (biology); Membrane protein; Cell; Cell membrane; Virus; Viral entry; Viral envelope; Virology; Intracellular; Membrane; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001232581,0.0002783141,0.0007231261,0.00007406706,0.0001526601,0.00002060032,0.0002479255,0.0002696145,0.0001017671],"category_scores_gemma":[0.00004595482,0.0001447109,0.0001238288,0.00008429959,0.0002717011,0.00004869407,0.0001891013,0.000237982,0.0002374205],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002538217,"about_ca_system_score_gemma":0.0001436564,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008150886,"about_ca_topic_score_gemma":0.00001919753,"domain_scores_codex":[0.998722,0.0002709289,0.0002730305,0.0003697003,0.00004947312,0.0003149085],"domain_scores_gemma":[0.9992077,0.0002687942,0.0001288636,0.0003069667,0.00003812767,0.00004959175],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002050306,0.0002347074,0.0001291406,0.00780081,0.000825632,0.00001902033,0.000381384,8.140439e-7,0.08717956,0.0001302098,0.004854393,0.8982393],"study_design_scores_gemma":[0.0006558512,0.0002895588,0.00001528684,0.003200201,0.0002455902,0.00007063714,0.00006769201,2.671509e-7,0.00614429,0.000004398507,0.9890846,0.0002216211],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01631653,0.9802833,0.000002959764,0.00004107923,0.00008419871,0.0005220014,0.002267064,0.00001273689,0.000470138],"genre_scores_gemma":[0.01063396,0.9868467,0.00001679294,0.00003096877,0.00001499161,0.00003714405,0.00005659777,0.00002220113,0.00234068],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9842302,"threshold_uncertainty_score":0.590114,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05185388920955003,"score_gpt":0.2977846293136427,"score_spread":0.2459307401040927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}