{"id":"W2292613782","doi":"10.1371/journal.pone.0144145","title":"Nuclear Receptor-Like Structure and Interaction of Congenital Heart Disease-Associated Factors GATA4 and NKX2-5","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Sydäntutkimussäätiö; Tekes; Academy of Finland; Foundation for Cardiovascular Research","keywords":"Zinc finger; Homeobox; GATA4; Transcription factor; Biology; Nuclear receptor; Genetics; Computational biology; Conserved sequence; Cell biology; Peptide sequence; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007882503,0.0003095091,0.0003398776,0.0001216976,0.0001884234,0.0002160569,0.000477786,0.000287529,0.001948041],"category_scores_gemma":[0.0001524078,0.0001176494,0.0002826939,0.00008061255,0.0001722487,0.0001499003,0.0001563965,0.0002286311,0.0003648603],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005905888,"about_ca_system_score_gemma":0.0003236255,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002403261,"about_ca_topic_score_gemma":0.001639004,"domain_scores_codex":[0.9999301,0.00001203342,0.000003045421,0.00001787391,0.00002326715,0.00001363562],"domain_scores_gemma":[0.999959,0.000006306856,0.000014373,0.000002379902,0.00000546612,0.00001241746],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001322305,0.0002013941,0.01549085,0.0003605286,0.0001530914,0.001810038,0.0001404904,0.04453502,0.921812,0.007174828,0.0009117686,0.006087827],"study_design_scores_gemma":[0.0006225923,0.001071114,0.04577494,0.0000657108,0.000266063,0.003224458,0.0003120367,0.5846069,0.3505055,0.002682483,0.01078042,0.00008782167],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941691,0.0006244176,0.003756981,0.00008046427,0.000015245,0.00001238533,0.0001424899,0.0000702239,0.001128669],"genre_scores_gemma":[0.9973927,0.0001265815,0.00169779,0.00002538595,0.000002421329,0.000007470876,0.0002537466,0.000005217855,0.0004887944],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002403261,"threshold_uncertainty_score":0.006516814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03748433325667844,"score_gpt":0.2634109020964255,"score_spread":0.225926568839747,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}