{"id":"W2292713941","doi":"10.1136/thoraxjnl-2015-207886","title":"Cigarette smokers have exaggerated alveolar barrier disruption in response to lipopolysaccharide inhalation","year":2016,"lang":"en","type":"article","venue":"Thorax","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Center for Tobacco Products; National Center for Advancing Translational Sciences; National Heart, Lung, and Blood Institute; National Institute on Alcohol Abuse and Alcoholism; National Cancer Institute; National Institutes of Health; Queen's University; Queen's University Belfast; China Scholarship Council; National Institute for Health and Care Research; Intensive Care Society; Medical Research Council; Public Health Agency","keywords":"Medicine; Bronchoalveolar lavage; ARDS; Inhalation; Inflammation; Smoke inhalation; Lung; Lipopolysaccharide; Vascular permeability; Internal medicine; Immunology; Pathology; Endocrinology; Gastroenterology; Anesthesia","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000262818,0.0002627286,0.0003366547,0.0002275236,0.0001719008,0.0003999397,0.0001644669,0.0004288333,0.001741977],"category_scores_gemma":[0.0003629805,0.0001955721,0.0002262309,0.000162259,0.0002918989,0.0001758896,0.0002672858,0.000469633,0.0004236694],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009934465,"about_ca_system_score_gemma":0.0001705155,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003342234,"about_ca_topic_score_gemma":0.0003653236,"domain_scores_codex":[0.9998275,0.00003833598,0.00001374483,0.00003808665,0.00005362173,0.00002869732],"domain_scores_gemma":[0.9997299,0.00004306119,0.0001050131,0.0000243563,0.00003459933,0.00006303281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003504031,0.0005643629,0.4988567,0.0002327257,0.0001720495,0.001025551,0.0002742883,0.00007822366,0.4857632,0.0001142783,0.0002634328,0.009151184],"study_design_scores_gemma":[0.00002142791,0.001693855,0.9803227,0.00001914644,0.0000847871,0.001767245,0.0001297555,0.0002032275,0.01504001,0.0001084795,0.00060225,0.000007267841],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981522,0.0008860827,0.0002884442,0.00008398039,0.00001698068,0.00003048663,0.0001350018,0.0000156907,0.0003910022],"genre_scores_gemma":[0.9983507,0.0005036489,0.000273048,0.00008431749,0.0000213508,0.00003161628,0.0002255924,0.00000385888,0.000505946],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001741977,"threshold_uncertainty_score":0.005827487,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04349530155187703,"score_gpt":0.379059858207574,"score_spread":0.335564556655697,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}