{"id":"W2292713941","doi":"10.1136/thoraxjnl-2015-207886","title":"Cigarette smokers have exaggerated alveolar barrier disruption in response to lipopolysaccharide inhalation","year":2016,"lang":"en","type":"article","venue":"Thorax","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Center for Tobacco Products; National Center for Advancing Translational Sciences; National Heart, Lung, and Blood Institute; National Institute on Alcohol Abuse and Alcoholism; National Cancer Institute; National Institutes of Health; Queen's University; Queen's University Belfast; China Scholarship Council; National Institute for Health and Care Research; Intensive Care Society; Medical Research Council; Public Health Agency","keywords":"Medicine; Bronchoalveolar lavage; ARDS; Inhalation; Inflammation; Smoke inhalation; Lung; Lipopolysaccharide; Vascular permeability; Internal medicine; Immunology; Pathology; Endocrinology; Gastroenterology; Anesthesia","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002140371,0.0001626317,0.0002586896,0.0005694385,0.00007169797,0.00002026507,0.0001150798,0.0001638941,0.0005325042],"category_scores_gemma":[0.003615042,0.0001073091,0.00005119178,0.0003884954,0.00006909987,0.0002130956,0.00007254281,0.0002936924,0.0004259275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000632692,"about_ca_system_score_gemma":0.0004500556,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001423859,"about_ca_topic_score_gemma":0.00009909732,"domain_scores_codex":[0.9975944,0.0004342899,0.0003998131,0.0004108041,0.0006373465,0.0005233836],"domain_scores_gemma":[0.9982705,0.0004397161,0.00005924354,0.0004824571,0.0001916261,0.0005564857],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0133616,0.00006553032,0.03229029,0.0000786521,0.00001918999,0.0002970745,0.0005155436,0.000003441888,0.7624955,0.00007439982,0.0005313226,0.1902675],"study_design_scores_gemma":[0.005026147,0.001772192,0.615352,0.001591828,0.00004157068,0.00005739379,0.0003306985,0.0002328154,0.2850407,0.0003056196,0.08968344,0.0005655385],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867247,0.0001902396,0.0003947538,0.01126107,0.00011911,0.0008589156,0.00002318589,0.00007816798,0.0003498579],"genre_scores_gemma":[0.9935001,0.00004025416,0.0001601171,0.001805133,0.0001244214,0.00009731814,0.000006174761,0.00004126321,0.004225221],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5830618,"threshold_uncertainty_score":0.5830547,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04349530155187703,"score_gpt":0.379059858207574,"score_spread":0.335564556655697,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}