{"id":"W2293414019","doi":"10.1096/fj.15-275552","title":"Aldosterone mediates metastatic spread of renal cancer <i>via</i> the G protein‐coupled estrogen receptor (GPER)","year":2016,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials; Memorial University of Newfoundland","funders":"Canadian Cancer Society","keywords":"Aldosterone; Endocrinology; Internal medicine; Mineralocorticoid receptor; GPER; Spironolactone; Cancer research; Estrogen receptor; Biology; Medicine; Cancer; Breast cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001298943,0.0002622533,0.0002833288,0.0001071238,0.0001265006,0.0003008776,0.0001401947,0.0001832126,0.0008274473],"category_scores_gemma":[0.0001051504,0.0001165171,0.0002718289,0.00005943381,0.000192705,0.0001881295,0.0001430535,0.0005180551,0.0002622531],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001741278,"about_ca_system_score_gemma":0.0002187702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001222552,"about_ca_topic_score_gemma":0.001684555,"domain_scores_codex":[0.9998885,0.0000267735,0.000007703887,0.00001551776,0.00002684992,0.00003462568],"domain_scores_gemma":[0.9999242,0.0000145149,0.00001814096,0.000007700502,0.000008778766,0.00002669427],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001590258,0.00002874515,0.0002918038,0.00002800204,0.000004059123,0.00006117614,0.00001771667,0.00003830398,0.99837,0.00007639889,0.0000341224,0.0008907679],"study_design_scores_gemma":[0.00004227388,0.000922794,0.01484205,0.000005610233,0.00002616562,0.0003932837,0.00008762233,0.0008690862,0.9808335,0.00009407535,0.001875098,0.00000841616],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995181,0.002035454,0.001315502,0.000157809,0.00002368179,0.00001217068,0.0001049709,0.00006612676,0.001103344],"genre_scores_gemma":[0.9974319,0.001024298,0.0004446581,0.00004307915,0.00001155085,0.00001017645,0.0001089331,0.000006369889,0.0009189697],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001222552,"threshold_uncertainty_score":0.002768159,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008559545667598685,"score_gpt":0.2369320647378025,"score_spread":0.2283725190702038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}