{"id":"W2293501830","doi":"10.1186/s12865-016-0142-3","title":"Illness progression in chronic fatigue syndrome: a shifting immune baseline","year":2016,"lang":"en","type":"article","venue":"BMC Immunology","topic":"Fibromyalgia and Chronic Fatigue Syndrome Research","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; National Institutes of Health; Clinical Science Research and Development; Eunice Kennedy Shriver National Institute of Child Health and Human Development; U.S. Public Health Service; National Institute on Alcohol Abuse and Alcoholism; Solve ME/CFS Initiative; U.S. Department of Veterans Affairs","keywords":"Chronic fatigue syndrome; Medicine; Internal medicine; Encephalomyelitis; Immune system; Immunology; Body mass index; Cytokine; Multiple sclerosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001437979,0.0002708851,0.000435627,0.0005552892,0.0002482973,0.0005287179,0.0001596796,0.0003485599,0.0007744051],"category_scores_gemma":[0.001995782,0.0001060865,0.0002633051,0.0003392848,0.0002766169,0.0003217781,0.0003948185,0.0005985706,0.000162917],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002237888,"about_ca_system_score_gemma":0.0002083713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007704334,"about_ca_topic_score_gemma":0.001223428,"domain_scores_codex":[0.9995903,0.0001183387,0.00003503618,0.0001192738,0.00008848179,0.00004843448],"domain_scores_gemma":[0.998755,0.0005464724,0.0003619937,0.00008768104,0.0001341024,0.0001148835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001256108,0.00006783805,0.9583028,0.00006919135,0.0000851885,0.0001193721,0.000245039,0.0005162868,0.01933701,0.00004274471,0.0001085026,0.01984992],"study_design_scores_gemma":[0.000009172863,0.0003507105,0.9973469,0.00001233034,0.0000273268,0.0002786029,0.000110164,0.0007329247,0.0008848748,0.00009941938,0.0001428848,0.00000450779],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985321,0.0004484269,0.0005919653,0.0000398675,0.000004225202,0.00001065712,0.0001123964,0.000008605383,0.0002519341],"genre_scores_gemma":[0.9990261,0.00008961173,0.0005408326,0.00002788111,0.00000776757,0.00001204079,0.0002247988,0.000002447642,0.0000686261],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001437979,"threshold_uncertainty_score":0.007604837,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03036908964219898,"score_gpt":0.3279277606457215,"score_spread":0.2975586710035225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}