{"id":"W2294465942","doi":"10.1021/jacs.6b00067","title":"Ratiometric Array of Conjugated Polymers–Fluorescent Protein Provides a Robust Mammalian Cell Sensor","year":2016,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":148,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Bone and Joint Health Institute; University of Calgary","funders":"National Institute of General Medical Sciences; European Commission","keywords":"Förster resonance energy transfer; Chemistry; Fluorescence; Green fluorescent protein; Biosensor; Conjugated system; Cell; Biophysics; Sensor array; Cell type; Nanotechnology; Polymer; Biochemistry; Gene; Biology; Materials science; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002152955,0.0001437062,0.0003007906,0.0000335187,0.00004182152,0.000009515213,0.0002952907,0.00007822263,0.000003032798],"category_scores_gemma":[0.000182497,0.00007202553,0.0005587989,0.000452656,0.000555962,0.000005516118,0.00007477294,0.0001297424,3.378219e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005235976,"about_ca_system_score_gemma":0.00008531731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001157941,"about_ca_topic_score_gemma":4.835385e-7,"domain_scores_codex":[0.9988964,0.00007446818,0.0004034103,0.0001706281,0.000259872,0.0001952857],"domain_scores_gemma":[0.9983929,0.00002547336,0.0009940997,0.0002645737,0.0002413208,0.00008158085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000119461,0.00009659355,0.0007515792,0.00001308712,0.00009477531,6.398265e-7,0.00001373468,0.000001229737,0.9950166,7.481538e-7,0.001268353,0.002623177],"study_design_scores_gemma":[0.0003477285,0.0002582447,0.0001861585,0.00004908282,0.00005578843,0.00001842925,0.0001194596,0.000004150069,0.9975504,0.00001459065,0.001278409,0.000117513],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951239,0.000126055,0.003140385,0.001417298,0.00002322423,0.0001125644,0.00001381272,0.000006968358,0.00003577667],"genre_scores_gemma":[0.9788385,0.0001150457,0.02034828,0.0002479884,0.0001593552,0.000001620926,0.000001695824,0.00001468325,0.000272855],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01720789,"threshold_uncertainty_score":0.2937116,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008136133821311451,"score_gpt":0.237581243021194,"score_spread":0.2294451091998825,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}