{"id":"W2294632132","doi":"10.1016/j.vaccine.2016.02.064","title":"Current status of synthetic hemozoin adjuvant: A preliminary safety evaluation","year":2016,"lang":"en","type":"review","venue":"Vaccine","topic":"Malaria Research and Control","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Japan Science and Technology Agency; Ministry of Health, British Columbia; Nippon Zenyaku Kogyo; Japan Agency for Medical Research and Development","keywords":"Adjuvant; Hemozoin; Immunoadjuvant; Vaccine adjuvant; Antigen; Potency; Medicine; Malaria; Immunology; Biology; Plasmodium falciparum; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009847162,0.000360321,0.002064245,0.0003813902,0.000036989,0.000007446644,0.0001866637,0.0001932846,0.00335156],"category_scores_gemma":[0.001382421,0.0002120135,0.0005091122,0.0002931944,0.00001398648,0.00004511532,0.0001128013,0.0004147433,0.0002919618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003683441,"about_ca_system_score_gemma":0.001842148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001353999,"about_ca_topic_score_gemma":0.000002906033,"domain_scores_codex":[0.9967603,0.0004272999,0.000908634,0.0004536685,0.0008581984,0.0005918904],"domain_scores_gemma":[0.9975863,0.0003912071,0.0004187174,0.0008290965,0.0004060195,0.0003686661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006335124,0.0001882587,0.00000981448,0.02049899,0.000210658,0.00001198042,0.00001326089,9.328107e-8,0.000003420756,0.0001495155,0.001280491,0.977],"study_design_scores_gemma":[0.003301795,0.0007980809,0.0003237505,0.04719446,0.002428763,0.00006709166,0.000002904554,0.0001212696,0.000004338714,0.00009057236,0.9454809,0.000186043],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000006530098,0.99435,0.0001569684,0.0004240897,0.0002351335,0.003502756,0.0001876708,0.00003172215,0.001105129],"genre_scores_gemma":[0.0004810344,0.99787,0.00003994198,0.00000917024,0.0003572054,0.0003439854,0.0003330085,0.00005437575,0.0005113251],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.976814,"threshold_uncertainty_score":0.9975595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05074868019188818,"score_gpt":0.3901502119973453,"score_spread":0.3394015318054571,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}