{"id":"W2294632132","doi":"10.1016/j.vaccine.2016.02.064","title":"Current status of synthetic hemozoin adjuvant: A preliminary safety evaluation","year":2016,"lang":"en","type":"review","venue":"Vaccine","topic":"Malaria Research and Control","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Japan Science and Technology Agency; Ministry of Health, British Columbia; Nippon Zenyaku Kogyo; Japan Agency for Medical Research and Development","keywords":"Adjuvant; Hemozoin; Immunoadjuvant; Vaccine adjuvant; Antigen; Potency; Medicine; Malaria; Immunology; Biology; Plasmodium falciparum; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009657633,0.0006964775,0.001587382,0.001259629,0.0001313359,0.0009365188,0.0006031776,0.0008998373,0.003176328],"category_scores_gemma":[0.0009778882,0.0002467661,0.0006158313,0.001030214,0.0003297972,0.001011779,0.0004657131,0.00113745,0.000739369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003824202,"about_ca_system_score_gemma":0.001561209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008723696,"about_ca_topic_score_gemma":0.001535345,"domain_scores_codex":[0.9998176,0.00003447561,0.00003749805,0.00002814716,0.0000609147,0.00002139647],"domain_scores_gemma":[0.999525,0.00024278,0.0000974883,0.00001020913,0.00009718892,0.00002735312],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000424978,0.0001536175,0.0002760541,0.04009638,0.0001512795,0.0001297466,0.00005117262,0.00035644,0.005712825,0.00135521,0.009852941,0.9414394],"study_design_scores_gemma":[0.0002600716,0.001397248,0.001902807,0.01271621,0.001352162,0.001309065,0.0001356799,0.000330316,0.005104573,0.001409619,0.9740381,0.00004414672],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003676167,0.9987887,0.000123488,0.0001685517,0.00008994425,0.00001080894,0.00003614955,0.000004590866,0.0004102526],"genre_scores_gemma":[0.0019017,0.997218,0.0002708008,0.0001930381,0.00007654806,0.00001154211,0.00004884073,0.000001030103,0.0002784848],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003176328,"threshold_uncertainty_score":0.0106259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05074868019188818,"score_gpt":0.3901502119973453,"score_spread":0.3394015318054571,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}