{"id":"W2294979059","doi":"10.3390/ph9010013","title":"Potential Use of Antimicrobial Peptides as Vaginal Spermicides/Microbicides","year":2016,"lang":"en","type":"review","venue":"Pharmaceuticals","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Bill and Melinda Gates Foundation","keywords":"Microbicide; Spermicide; Microbicides for sexually transmitted diseases; Vaginal microbicide; Vagina; Antimicrobial peptides; Antimicrobial; Cathelicidin; Medicine; Population; Microbiology; Immunology; Pharmacology; Biology; Family planning; Research methodology; Human immunodeficiency virus (HIV); Surgery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000381797,0.001093686,0.003358495,0.000487109,0.0002478781,0.000102757,0.0008095797,0.0009770578,0.003828408],"category_scores_gemma":[0.0001810757,0.0007987458,0.001552859,0.0002676301,0.001540411,0.0004504073,0.000544597,0.001020889,0.005229905],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001196526,"about_ca_system_score_gemma":0.0004663268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000108025,"about_ca_topic_score_gemma":0.000002065425,"domain_scores_codex":[0.9954615,0.0007054197,0.00159654,0.0009679874,0.0001021605,0.001166412],"domain_scores_gemma":[0.9972217,0.0008484006,0.0009449391,0.0006903126,0.0001871468,0.0001075057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002022977,0.0004012047,0.000009073415,0.007731839,0.002031346,0.00009968833,0.00005278486,0.000001313322,0.2945341,0.0009496965,0.03932085,0.6546658],"study_design_scores_gemma":[0.0007520114,0.00009075141,0.0000013907,0.01132189,0.001843981,0.001351561,0.00001078914,2.076811e-7,0.05601516,0.00004518693,0.9276985,0.0008686024],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008862516,0.9937974,0.0001424025,0.0001179268,0.001722926,0.001044453,0.001545596,0.0001608715,0.00058216],"genre_scores_gemma":[0.002932821,0.9873106,0.0002676109,0.0003457311,0.0003086809,0.00002871204,0.0003783221,0.0001694195,0.008258034],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8883776,"threshold_uncertainty_score":0.9994463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07946023487507468,"score_gpt":0.3684793727436552,"score_spread":0.2890191378685805,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}