{"id":"W2295116138","doi":"10.1517/14656566.2015.1064897","title":"Odanacatib for the treatment of osteoporosis","year":2015,"lang":"en","type":"review","venue":"Expert Opinion on Pharmacotherapy","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; University Health Network; Mount Sinai Hospital; University of Toronto","funders":"","keywords":"Cathepsin K; Medicine; Osteoporosis; Bone resorption; Bone mineral; Pharmacology; Internal medicine; Osteoclast; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034099,0.00052213,0.0007771038,0.001274614,0.0002245161,0.000741371,0.0006643039,0.0009473645,0.01132488],"category_scores_gemma":[0.0005567062,0.0001530661,0.0006047923,0.001039776,0.0002559313,0.0005939741,0.0005151859,0.001716857,0.005445857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004806036,"about_ca_system_score_gemma":0.0008465601,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000832263,"about_ca_topic_score_gemma":0.002264641,"domain_scores_codex":[0.9998212,0.00002982579,0.00001944562,0.00003030167,0.00008129278,0.0000179601],"domain_scores_gemma":[0.9998376,0.00004906622,0.00003933571,0.000004150234,0.00004838339,0.00002143825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000107695,0.00004491844,0.00008432961,0.01178075,0.000106921,0.0001787786,0.00002747124,0.0001793449,0.001682652,0.002779172,0.1075342,0.8754939],"study_design_scores_gemma":[0.00005921119,0.00007600077,0.0003374962,0.002913271,0.00008298459,0.0009922418,0.00001526608,0.00005973042,0.0003132475,0.001376015,0.9937643,0.00001015684],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002073725,0.9915459,0.0001725353,0.001427152,0.0009442362,0.00002198872,0.0001113168,0.00002342807,0.005546111],"genre_scores_gemma":[0.001786857,0.9916767,0.0002349127,0.001620869,0.0006822245,0.00001935023,0.000211044,0.000004398446,0.003763691],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01132488,"threshold_uncertainty_score":0.03788549,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.11406651901763,"score_gpt":0.4488779770347258,"score_spread":0.3348114580170958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}