{"id":"W2295326929","doi":"10.1016/j.stem.2016.01.022","title":"CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs","year":2016,"lang":"en","type":"article","venue":"Cell stem cell","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":549,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Biomedical Imaging and Bioengineering; Howard Hughes Medical Institute; National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institutes of Health; Canadian Institutes of Health Research; Innovative Genomics Institute; University of California, San Francisco; Center for AIDS Research, University of Washington; National Heart, Lung, and Blood Institute; Gladstone Institutes; National Institute on Drug Abuse","keywords":"Biology; CRISPR; CRISPR interference; Induced pluripotent stem cell; Gene silencing; Cas9; Genome editing; RNA interference; Psychological repression; Regulation of gene expression; Gene expression; Gene; Cell biology; Gene knockdown; Genetics; Computational biology; Transcription activator-like effector nuclease; Embryonic stem cell; RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01143742308508977,"score_gpt":0.2475092689672364,"score_spread":0.2360718458821466,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}