{"id":"W2295370294","doi":"10.1161/atvb.34.suppl_1.531","title":"Abstract 531: Mutagenic Gene Trapping to Study Novel Genes in Zebrafish Cardiovascular Development","year":2014,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; University of Toronto","funders":"","keywords":"Biology; Zebrafish; TBX1; Cre recombinase; Gene; Genetics; Phenotype; Brachyury; Notochord; Locus (genetics); Embryonic stem cell; Cell biology; Molecular biology; Embryogenesis; Gene expression; Promoter; Mesoderm; Transgene; Genetically modified mouse","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001987762,0.0005829075,0.0002905648,0.000523068,0.0002698682,0.0002032316,0.0003749586,0.0005373104,0.003050837],"category_scores_gemma":[0.0001430469,0.0002733404,0.0003594884,0.0001978798,0.0003129253,0.0002302295,0.0003227567,0.0007283377,0.0009932488],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004087303,"about_ca_system_score_gemma":0.0003350082,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001240335,"about_ca_topic_score_gemma":0.001653396,"domain_scores_codex":[0.9997784,0.00001897393,0.00002173371,0.00006212319,0.00008571168,0.00003303912],"domain_scores_gemma":[0.999895,0.00001893781,0.0000394835,0.00001314018,0.00001434134,0.00001919413],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009462136,0.000007274577,0.00007446558,0.00002046896,0.00000168848,0.00004294237,0.000007298842,0.00002768673,0.9990557,0.0000871208,0.00004244091,0.0006234832],"study_design_scores_gemma":[0.0000232543,0.0002548411,0.004676506,0.0000157189,0.00002354714,0.001006555,0.00001877864,0.000879514,0.9881776,0.00005936434,0.004853885,0.00001037879],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8986561,0.002716856,0.08411387,0.000461117,0.0001432623,0.0004590321,0.002953469,0.0008108455,0.009685467],"genre_scores_gemma":[0.9249288,0.00220834,0.0471746,0.0002625668,0.00003316252,0.000454615,0.003252323,0.0003286743,0.02135679],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003050837,"threshold_uncertainty_score":0.01020604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04355041181779467,"score_gpt":0.294365891323612,"score_spread":0.2508154795058173,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}