{"id":"W2295595360","doi":"10.1111/vox.12390","title":"Manufacturing method affects mitochondrial <scp>DNA</scp> release and extracellular vesicle composition in stored red blood cells","year":2016,"lang":"en","type":"article","venue":"Vox Sanguinis","topic":"Blood transfusion and management","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Blood Services; University of Alberta","funders":"National Heart, Lung, and Blood Institute; Canadian Blood Services; Blood Systems Research Institute","keywords":"Flow cytometry; Apheresis; Extracellular vesicles; Mitochondrial DNA; Biology; Extracellular vesicle; Extracellular; Andrology; Cold storage; Red blood cell; Platelet; Cell biology; Molecular biology; Immunology; Biochemistry; Microvesicles; Medicine; Gene; microRNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001150199,0.0002711709,0.0002602413,0.0003681543,0.0001897094,0.0008585807,0.0003164792,0.0003444998,0.001429887],"category_scores_gemma":[0.001993991,0.0001896726,0.0003634991,0.0003444645,0.0003216551,0.0004745328,0.0003738306,0.0003499845,0.0003761239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000265247,"about_ca_system_score_gemma":0.0001495435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003395236,"about_ca_topic_score_gemma":0.000335651,"domain_scores_codex":[0.9987005,0.00031,0.0002350372,0.0002685297,0.000381268,0.0001047781],"domain_scores_gemma":[0.9982357,0.000580542,0.0006669081,0.0001541257,0.0002944722,0.00006820598],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001275647,0.00012477,0.01231767,0.0002484376,0.00008706776,0.00009162154,0.0001642678,0.000222227,0.9774927,0.00004012027,0.00007583981,0.007859689],"study_design_scores_gemma":[0.00002196041,0.00171253,0.08041085,0.00003929533,0.000162607,0.0003181773,0.0001579826,0.0006831452,0.9151849,0.00003450603,0.001252236,0.00002184503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961001,0.002040239,0.0012102,0.00002962308,0.00002127811,0.0000287168,0.0001992254,0.00002203772,0.0003485784],"genre_scores_gemma":[0.9963979,0.0006727634,0.001990753,0.00005899352,0.00001522318,0.00003999086,0.0003433311,0.00002472861,0.0004565225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001429887,"threshold_uncertainty_score":0.006082952,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009091035744980979,"score_gpt":0.2396132516985937,"score_spread":0.2305222159536127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}