{"id":"W2295641663","doi":"10.1128/jvi.03010-15","title":"DDX3 Interacts with Influenza A Virus NS1 and NP Proteins and Exerts Antiviral Function through Regulation of Stress Granule Formation","year":2016,"lang":"en","type":"article","venue":"Journal of Virology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Biology; Virus; Viral life cycle; Virology; Influenza A virus; Stress granule; Helicase; RNA Helicase A; Immunoprecipitation; VP40; Ribonucleoprotein; Viral matrix protein; Viral replication; Cell biology; RNA; Gene; Genetics; Messenger RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001724662,0.00006480066,0.0001252792,0.00005652068,0.00003214433,0.000009062347,0.00003973646,0.00007538817,0.000003713819],"category_scores_gemma":[0.00006070176,0.00003871277,0.00002052742,0.00002927713,0.00009340105,0.00004971156,0.00003125689,0.00005929047,2.958773e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007388677,"about_ca_system_score_gemma":0.00002455635,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001370974,"about_ca_topic_score_gemma":0.00006700289,"domain_scores_codex":[0.9994323,0.00006522065,0.0002105352,0.00008328704,0.00009338553,0.0001152797],"domain_scores_gemma":[0.999507,0.00001638073,0.0002516291,0.00007335399,0.0001151373,0.00003652677],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001614111,0.00002792174,0.006219267,0.00002261119,0.00003232775,0.000002471027,0.00006816677,0.000006192422,0.9842895,0.00003741287,0.00005889151,0.007621078],"study_design_scores_gemma":[0.001893461,0.003708848,0.06865589,0.00008782242,0.0000221506,0.0001801981,0.0000438048,0.00004163302,0.9238996,0.0004403734,0.0009576025,0.00006862557],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883038,0.0002888034,0.01101758,0.0002138019,0.00002507968,0.00009378428,0.000004063132,0.00000120491,0.00005181929],"genre_scores_gemma":[0.9992037,0.000251271,0.0003473253,0.00008052073,0.00006486789,0.000002227195,0.000002423597,0.00000552611,0.0000421064],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06243662,"threshold_uncertainty_score":0.1578661,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01083615244857169,"score_gpt":0.2620385446002168,"score_spread":0.2512023921516451,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}