{"id":"W2296232579","doi":"10.1107/s2059798315022111","title":"Re-refinement of the spliceosomal U4 snRNP core-domain structure","year":2015,"lang":"en","type":"article","venue":"Acta Crystallographica Section D Structural Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Medical Research Council; European Synchrotron Radiation Facility","keywords":"snRNP; Small nuclear ribonucleoprotein; Ribonucleoprotein; Sequence (biology); Computational biology; Biology; Domain (mathematical analysis); Janus; Biophysics; RNA; Physics; Crystallography; Genetics; Chemistry; Nanotechnology; Materials science; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002010602,0.0002307074,0.0002362039,0.0001153488,0.0001717143,0.00001753544,0.0004674502,0.0003414757,0.00006124796],"category_scores_gemma":[0.0001580787,0.0001508383,0.0001899091,0.0003855462,0.0004463992,0.000007682614,0.000286671,0.0002744399,1.672596e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000262251,"about_ca_system_score_gemma":0.0001093087,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002078454,"about_ca_topic_score_gemma":0.001141202,"domain_scores_codex":[0.9984044,0.0001938657,0.0003370974,0.000435549,0.0002128104,0.0004163133],"domain_scores_gemma":[0.9988158,0.00002020537,0.0002088156,0.0005768964,0.0002128571,0.000165374],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002286621,0.000009515566,0.05346252,0.00001103435,0.00009438603,8.665229e-7,0.0000534198,0.00002177574,0.9444072,0.0002815066,0.001143304,0.0002858702],"study_design_scores_gemma":[0.008402837,0.006641862,0.3637997,0.00006497989,0.0001541276,0.0004946855,0.003057002,0.0003826459,0.2147322,0.03168963,0.3687197,0.001860735],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975613,0.0002294155,0.00006539924,0.0006985453,0.0006792869,0.0003088992,0.00008503055,0.00001888036,0.0003532564],"genre_scores_gemma":[0.9986444,0.00003358223,0.0003659546,0.0002322043,0.0003535636,0.00001244212,0.0001698813,0.00001835829,0.000169639],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.729675,"threshold_uncertainty_score":0.6151007,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0165317548003641,"score_gpt":0.2712431276146635,"score_spread":0.2547113728142994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}