{"id":"W2296348514","doi":"10.1016/j.matbio.2016.03.002","title":"Laminin γ2 knockout mice rescued with the human protein exhibit enamel maturation defects","year":2016,"lang":"en","type":"article","venue":"Matrix Biology","topic":"Bone and Dental Protein Studies","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Shriners Hospitals for Children - Canada; Université de Montréal","funders":"National Heart, Lung, and Blood Institute; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health; Réseau de Recherche en Santé Buccodentaire et Osseuse","keywords":"Ameloblast; Enamel paint; Laminin; Amelogenin; Knockout mouse; Cell biology; Basement membrane; Enamel organ; Extracellular matrix; Biology; Dentistry; Medicine; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002897338,0.001012182,0.0003508503,0.001035341,0.0003619887,0.0005209558,0.0003101628,0.0007612246,0.004962076],"category_scores_gemma":[0.0001773035,0.000355915,0.0004176264,0.0003373855,0.0007547577,0.0003150754,0.0004448366,0.000930223,0.001054378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000343088,"about_ca_system_score_gemma":0.000367009,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001177596,"about_ca_topic_score_gemma":0.001898887,"domain_scores_codex":[0.9997292,0.0000321441,0.00003639549,0.00007228244,0.0000838427,0.00004605005],"domain_scores_gemma":[0.9996781,0.00004625725,0.0001392343,0.00003414864,0.00002320468,0.00007900972],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001264073,0.00001077026,0.0001902643,0.00002002909,0.000009386836,0.0003719778,0.0000319348,0.0000599386,0.9982793,0.0002666987,0.00006233301,0.0005708927],"study_design_scores_gemma":[0.00002587188,0.0001091572,0.004122604,0.00001286262,0.00005866437,0.002061336,0.0001262991,0.0003781267,0.9889354,0.0001842746,0.003974046,0.00001129089],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9813979,0.001539397,0.009873386,0.0003186744,0.0001252822,0.0000314454,0.00142478,0.0004478044,0.004841373],"genre_scores_gemma":[0.9736125,0.001376763,0.005237037,0.0001088276,0.000016281,0.0000420958,0.0009700251,0.0001930821,0.01844344],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004962076,"threshold_uncertainty_score":0.01659983,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01425496477368889,"score_gpt":0.2850239904850439,"score_spread":0.270769025711355,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}