{"id":"W2298072787","doi":"10.1097/qai.0000000000000993","title":"PrEP Adherence Patterns Strongly Affect Individual HIV Risk and Observed Efficacy in Randomized Clinical Trials","year":2016,"lang":"en","type":"article","venue":"JAIDS Journal of Acquired Immune Deficiency Syndromes","topic":"HIV/AIDS Research and Interventions","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Pill; Medicine; Pre-exposure prophylaxis; Randomized controlled trial; Human immunodeficiency virus (HIV); Clinical trial; Affect (linguistics); Internal medicine; Men who have sex with men; Family medicine; Pharmacology; Psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.2653995,0.001455891,0.004063261,0.001057192,0.0005828919,0.003919803,0.001992447,0.003629758,0.003989278],"category_scores_gemma":[0.3737465,0.001417081,0.008911578,0.001534092,0.002560173,0.003699627,0.001570244,0.003259399,0.0004456513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002127239,"about_ca_system_score_gemma":0.003781288,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00111032,"about_ca_topic_score_gemma":0.0007290926,"domain_scores_codex":[0.6365421,0.3338352,0.01337551,0.009050746,0.00543046,0.001766029],"domain_scores_gemma":[0.4858495,0.4467998,0.04165644,0.02054835,0.00393956,0.001206276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"observational","study_design_scores_codex":[0.072125,0.002089577,0.2023772,0.01704421,0.1189421,0.001096269,0.001229419,0.3861863,0.002155424,0.05324635,0.007819071,0.1356891],"study_design_scores_gemma":[0.0507186,0.02355427,0.06824805,0.006919404,0.06140367,0.0009899684,0.0003746027,0.578476,0.004021456,0.1890062,0.01584543,0.0004424502],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5720758,0.06099458,0.309432,0.01653043,0.002188873,0.01505555,0.00418484,0.001008996,0.01852901],"genre_scores_gemma":[0.9613664,0.002131257,0.02781964,0.001499817,0.0001413199,0.005806847,0.0005162271,0.00005724681,0.0006612573],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2653995,"threshold_uncertainty_score":0.9058932,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.124376135067356,"score_gpt":0.4144930572145544,"score_spread":0.2901169221471984,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}