{"id":"W2298072787","doi":"10.1097/qai.0000000000000993","title":"PrEP Adherence Patterns Strongly Affect Individual HIV Risk and Observed Efficacy in Randomized Clinical Trials","year":2016,"lang":"en","type":"article","venue":"JAIDS Journal of Acquired Immune Deficiency Syndromes","topic":"HIV/AIDS Research and Interventions","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Pill; Medicine; Pre-exposure prophylaxis; Randomized controlled trial; Human immunodeficiency virus (HIV); Clinical trial; Affect (linguistics); Internal medicine; Men who have sex with men; Family medicine; Pharmacology; Psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.0401806,0.0003072744,0.002984112,0.0009016601,0.0001091569,0.00009732455,0.0004945092,0.0002079968,0.0004967363],"category_scores_gemma":[0.06823028,0.0001698704,0.001658587,0.0005083242,0.0005572233,0.0005013757,0.0001812117,0.000410364,0.0000666213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008029381,"about_ca_system_score_gemma":0.0003252814,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007441208,"about_ca_topic_score_gemma":0.00001002869,"domain_scores_codex":[0.9875643,0.006545799,0.003954468,0.0003895774,0.0009257416,0.0006201691],"domain_scores_gemma":[0.9844996,0.0124207,0.001836254,0.0005000421,0.0003497143,0.0003937257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.06481316,0.003834227,0.5093624,0.0003402402,0.002119621,0.0007597795,0.001133525,0.000008504773,0.01113933,0.0001427398,0.003241539,0.4031049],"study_design_scores_gemma":[0.2458748,0.01162498,0.7345237,0.004077186,0.0008619311,0.0007412116,0.0005465551,0.0002493916,0.0009355876,0.0001832031,0.00009149588,0.0002900083],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894809,0.005610434,0.002634602,0.0006080006,0.0003126579,0.001101366,0.00009463167,0.00003293282,0.0001245422],"genre_scores_gemma":[0.9927474,0.004856614,0.0005349671,0.00001089569,0.0001166726,0.00003243005,0.000009106559,0.00003480626,0.001657108],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4028149,"threshold_uncertainty_score":0.988336,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.124376135067356,"score_gpt":0.4144930572145544,"score_spread":0.2901169221471984,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}