{"id":"W2298301162","doi":"10.4049/jimmunol.188.supp.126.19","title":"Calcineurin inhibitor (CNI) use in pediatric liver and kidney transplant (Tx) patients is associated with increased risk of obesity and impaired T-regulatory (Treg) cell function. (126.19)","year":2012,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; Calcineurin; Overweight; Internal medicine; Endocrinology; Renal function; Obesity; Gastroenterology; Transplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003243097,0.0002177742,0.0002914243,0.0003976909,0.0002600743,0.0003897075,0.0001357874,0.0001902308,0.001358602],"category_scores_gemma":[0.001027882,0.000125977,0.0002620594,0.0008143286,0.0002415981,0.0002549998,0.0002085197,0.0004927673,0.0001348462],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000235035,"about_ca_system_score_gemma":0.0003075342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001301461,"about_ca_topic_score_gemma":0.001904976,"domain_scores_codex":[0.9997161,0.00005928659,0.00003518361,0.00005743547,0.00007916342,0.00005285031],"domain_scores_gemma":[0.9983763,0.0002310987,0.00109945,0.00003764554,0.00005278622,0.0002027128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001095238,0.00001407835,0.9976901,0.000008295703,0.00001513662,0.0001204569,0.00001375065,0.0000177639,0.0004009349,0.000008388721,0.00003749767,0.00156417],"study_design_scores_gemma":[0.000006038898,0.0002033828,0.9972108,0.000008101556,0.00003411986,0.001873965,0.00005815108,0.0001195984,0.0003203172,0.00001248567,0.0001512243,0.000001924343],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992179,0.0003774982,0.00006122809,0.00002323524,0.000002754167,0.000002497268,0.0001004362,0.000002802399,0.0002116964],"genre_scores_gemma":[0.9994925,0.0001857837,0.0001023107,0.00001700504,0.000007747449,0.000003490631,0.0001383282,0.000001536086,0.00005128001],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001358602,"threshold_uncertainty_score":0.004544973,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006161913355729007,"score_gpt":0.1795058509450241,"score_spread":0.1733439375892951,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}