{"id":"W2299076631","doi":"10.1371/journal.pbio.1002416","title":"MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition Zone","year":2016,"lang":"en","type":"article","venue":"PLoS Biology","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":136,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; Conseil régional de Bourgogne-Franche-Comté; National Institute of General Medical Sciences; GIS-Institut des Maladies Rares; Michael Smith Health Research BC; National Institutes of Health; March of Dimes Foundation; Science Foundation Ireland; Canadian Institutes of Health Research; David and Lucile Packard Foundation","keywords":"Ciliogenesis; Biology; Cilium; Caenorhabditis elegans; Ciliopathy; Genetics; Cell biology; Centrosome; Gene; Phenotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003791528,0.0002328568,0.00009692122,0.0001011844,0.0001376922,0.0001489954,0.0001444789,0.0001603194,0.0008603308],"category_scores_gemma":[0.00007541264,0.0001130703,0.0001773079,0.00004048177,0.0001309663,0.0001470345,0.0002521163,0.0002590705,0.0004612979],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000350298,"about_ca_system_score_gemma":0.0001997499,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001074504,"about_ca_topic_score_gemma":0.00142369,"domain_scores_codex":[0.9999413,0.000003414586,0.000003951628,0.00001542312,0.00001878364,0.00001702389],"domain_scores_gemma":[0.9999374,0.000003350586,0.00001927303,0.000005681954,0.00000791273,0.00002639993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000487507,0.000003660549,0.0003554489,0.00001665818,0.000001408634,0.00008563263,0.000006443859,0.00002892913,0.9988011,0.0001104184,0.00002753361,0.000514009],"study_design_scores_gemma":[0.00001243708,0.00007089023,0.02358681,0.000004346443,0.000007935351,0.0005142147,0.00002604754,0.00167027,0.9713436,0.0000494353,0.002708658,0.000005291112],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959584,0.0005122641,0.001881781,0.00004891637,0.0000108266,0.00001106691,0.0002379016,0.00005395405,0.001285024],"genre_scores_gemma":[0.9948549,0.0001941285,0.00177546,0.00002572303,0.000002457545,0.00001115572,0.0006220674,0.00001117442,0.002502846],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001074504,"threshold_uncertainty_score":0.002878129,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007254384367831685,"score_gpt":0.2022281624028985,"score_spread":0.1949737780350668,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}