{"id":"W2299076631","doi":"10.1371/journal.pbio.1002416","title":"MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition Zone","year":2016,"lang":"en","type":"article","venue":"PLoS Biology","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":136,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; Conseil régional de Bourgogne-Franche-Comté; National Institute of General Medical Sciences; GIS-Institut des Maladies Rares; Michael Smith Health Research BC; National Institutes of Health; March of Dimes Foundation; Science Foundation Ireland; Canadian Institutes of Health Research; David and Lucile Packard Foundation","keywords":"Ciliogenesis; Biology; Cilium; Caenorhabditis elegans; Ciliopathy; Genetics; Cell biology; Centrosome; Gene; Phenotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006063839,0.00009003273,0.0001055582,0.00001470991,0.00003572471,0.000002228432,0.00011714,0.0001247379,0.00002333214],"category_scores_gemma":[0.00006247236,0.00004885115,0.00005560684,0.00002498591,0.0001537969,0.000001338992,0.00006877282,0.00002548269,0.000004292634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003791837,"about_ca_system_score_gemma":0.00005561024,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008485504,"about_ca_topic_score_gemma":0.00001231667,"domain_scores_codex":[0.9993667,0.00009542025,0.0001293186,0.0002183181,0.00004930724,0.0001409488],"domain_scores_gemma":[0.9996014,0.00001642512,0.00005046064,0.0002305805,0.00004195392,0.00005918573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004734717,0.00005781144,0.005798662,0.00001243879,0.00003797941,4.745256e-7,0.00001784132,3.459072e-7,0.9915164,0.00006245977,0.0001595064,0.002288722],"study_design_scores_gemma":[0.0005380957,0.0002059424,0.01851816,0.0000185438,0.00002798102,0.00000988916,0.00002852227,0.000003389189,0.9774678,0.0002697901,0.002818241,0.00009358875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963894,0.0007862563,0.001392195,0.0007600369,0.0000802593,0.0001205207,0.0001378681,0.000005539982,0.0003279104],"genre_scores_gemma":[0.9990054,0.0002472752,0.00008495746,0.0003154115,0.00007865597,0.00001412923,0.00002333975,0.000007691375,0.0002231734],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01404855,"threshold_uncertainty_score":0.1992092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007254384367831685,"score_gpt":0.2022281624028985,"score_spread":0.1949737780350668,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}