{"id":"W2299098537","doi":"10.1016/j.celrep.2016.02.071","title":"Chemokine Signaling Enhances CD36 Responsiveness toward Oxidized Low-Density Lipoproteins and Accelerates Foam Cell Formation","year":2016,"lang":"en","type":"article","venue":"Cell Reports","topic":"Atherosclerosis and Cardiovascular Diseases","field":"Immunology and Microbiology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; Toronto Metropolitan University; Hospital for Sick Children; Ontario Institute for Cancer Research; University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"CD36; Scavenger receptor; Cell biology; Foam cell; Chemokine; Chemokine receptor; Integrin; Chemistry; Actin; Actin cytoskeleton; Cytoskeleton; Receptor; Cell; Biology; Biochemistry; Lipoprotein; Cholesterol","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002430931,0.0002824689,0.0004111728,0.0002760589,0.0001501555,0.0003338114,0.0001099625,0.0003262973,0.001322136],"category_scores_gemma":[0.0001571927,0.0001429562,0.0002103876,0.0001361566,0.0002114422,0.0002130461,0.0001977793,0.0004757625,0.000444538],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003059586,"about_ca_system_score_gemma":0.000286067,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004505655,"about_ca_topic_score_gemma":0.0005382631,"domain_scores_codex":[0.9997374,0.00005842148,0.00001525589,0.00002733015,0.00004081566,0.0001207425],"domain_scores_gemma":[0.9998688,0.00001686699,0.00002381782,0.00001035476,0.0000189687,0.00006124969],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002256395,0.00003364493,0.0001147543,0.00002009328,0.000001386017,0.00005002879,0.00001527913,0.00001599349,0.9987814,0.00006519306,0.00003910836,0.0006374773],"study_design_scores_gemma":[0.00004620804,0.0007294577,0.007497169,0.00000813253,0.00001622171,0.000327829,0.00004646372,0.0009612181,0.9878543,0.0001000277,0.002405326,0.000007624613],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968393,0.001365192,0.000790623,0.000144182,0.00003155827,0.00001631814,0.00009300268,0.00005376087,0.000666038],"genre_scores_gemma":[0.9965799,0.0005941904,0.0008548047,0.00006945448,0.00002501284,0.00002362069,0.000117686,0.000009696741,0.001725433],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001322136,"threshold_uncertainty_score":0.004423022,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01191271307801759,"score_gpt":0.2074389702774176,"score_spread":0.1955262571994001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}