{"id":"W2299098537","doi":"10.1016/j.celrep.2016.02.071","title":"Chemokine Signaling Enhances CD36 Responsiveness toward Oxidized Low-Density Lipoproteins and Accelerates Foam Cell Formation","year":2016,"lang":"en","type":"article","venue":"Cell Reports","topic":"Atherosclerosis and Cardiovascular Diseases","field":"Immunology and Microbiology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; Toronto Metropolitan University; Hospital for Sick Children; Ontario Institute for Cancer Research; University of Toronto","funders":"Canadian Institutes of Health Research; Hospital for Sick Children; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"CD36; Scavenger receptor; Cell biology; Foam cell; Chemokine; Chemokine receptor; Integrin; Chemistry; Actin; Actin cytoskeleton; Cytoskeleton; Receptor; Cell; Biology; Biochemistry; Lipoprotein; Cholesterol","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004532585,0.0002052921,0.0003580078,0.00005309488,0.0001932589,0.00003624104,0.00008311271,0.0001917221,0.0002209828],"category_scores_gemma":[0.00009444448,0.0001426865,0.0001987598,0.00007291513,0.0001305744,0.0002313286,0.00009722753,0.00008868203,0.00005616698],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003738428,"about_ca_system_score_gemma":0.00005798737,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003209796,"about_ca_topic_score_gemma":0.000003189041,"domain_scores_codex":[0.9986833,0.0001609163,0.0003834399,0.0004052546,0.00007479831,0.0002922355],"domain_scores_gemma":[0.9990662,0.00008626278,0.0002884887,0.0003687702,0.0001436082,0.00004672262],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001357271,0.00007666238,0.0008753302,0.00007617888,0.00005245507,0.00004074412,0.0001952354,0.000001177795,0.9943297,0.0000023009,0.0002274573,0.003987025],"study_design_scores_gemma":[0.0008263434,0.00006170482,0.006893468,0.0001092772,0.00008469589,0.00009518446,0.0001477891,3.747388e-7,0.987772,0.000126948,0.003662695,0.000219454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905398,0.006893616,0.001447016,0.00007243151,0.0003185905,0.0003207322,0.000007503946,0.00008161783,0.0003186543],"genre_scores_gemma":[0.997884,0.0007076554,0.00006027912,0.00005515862,0.00005153431,0.00004412318,0.00003249516,0.00002042368,0.00114438],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007344113,"threshold_uncertainty_score":0.5818588,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01191271307801759,"score_gpt":0.2074389702774176,"score_spread":0.1955262571994001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}