{"id":"W2299985318","doi":"10.1021/acscombsci.5b00198","title":"What is a “DNA-Compatible” Reaction?","year":2016,"lang":"en","type":"article","venue":"ACS Combinatorial Science","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":205,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"NIH Office of the Director; Natural Sciences and Engineering Research Council of Canada; Defense Advanced Research Projects Agency; National Institutes of Health","keywords":"Chemistry; DNA; Combinatorial chemistry; Computational biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004062388,0.001123695,0.001315747,0.0008694432,0.0007717877,0.003419446,0.0009791907,0.002300615,0.003052552],"category_scores_gemma":[0.008818808,0.0006414079,0.0007507671,0.0009306028,0.003167272,0.005777324,0.0009131774,0.001963048,0.002567868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001367173,"about_ca_system_score_gemma":0.002059734,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000435549,"about_ca_topic_score_gemma":0.0006503087,"domain_scores_codex":[0.9970747,0.0007615159,0.0002749679,0.000656612,0.0009819061,0.0002503198],"domain_scores_gemma":[0.9966171,0.001226897,0.0008079048,0.0003900832,0.00051947,0.0004385842],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0008791257,0.0007457473,0.006556718,0.007086109,0.0003158253,0.002219526,0.0007947407,0.006998599,0.4499389,0.2974544,0.005993071,0.2210173],"study_design_scores_gemma":[0.0001173322,0.001638928,0.0017061,0.0008839651,0.0002628107,0.003413677,0.001080508,0.008853678,0.6344702,0.1469794,0.200353,0.0002404666],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.2706142,0.07891078,0.5453446,0.03487444,0.004037523,0.00110137,0.00149794,0.001885588,0.06173357],"genre_scores_gemma":[0.6931947,0.03104233,0.255823,0.006779726,0.000768166,0.0005969238,0.0008276345,0.0006152522,0.01035223],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.004062388,"threshold_uncertainty_score":0.0214842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007891952906983392,"score_gpt":0.253829741847994,"score_spread":0.2459377889410106,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}