{"id":"W2300170640","doi":"10.1186/s13075-016-0965-6","title":"Cartilage-specific deletion of ephrin-B2 in mice results in early developmental defects and an osteoarthritis-like phenotype during aging in vivo","year":2016,"lang":"en","type":"article","venue":"Arthritis Research & Therapy","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Saint-Luc; Toronto Rehabilitation Institute; University Health Network; University of Toronto; Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research; Shriners Hospitals for Children; McGill University","keywords":"Cartilage; Osteoarthritis; In vivo; Pathology; Genetically modified mouse; Ossification; Endocrinology; Internal medicine; Biology; Medicine; Anatomy; Transgene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003418574,0.001031557,0.0004930353,0.00117319,0.0003332369,0.0004498308,0.0003963422,0.0009052119,0.003539875],"category_scores_gemma":[0.0001726458,0.0005579346,0.0005311805,0.000349176,0.000522311,0.0004082394,0.0004750204,0.0009298172,0.001420133],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000355004,"about_ca_system_score_gemma":0.0003262678,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006483117,"about_ca_topic_score_gemma":0.001335414,"domain_scores_codex":[0.9995595,0.000046491,0.00007095098,0.000115405,0.0001344029,0.00007335081],"domain_scores_gemma":[0.9994509,0.00003224856,0.0002552201,0.00003724726,0.000038288,0.0001862027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001344557,0.00003707628,0.0002479192,0.00003347407,0.000009127863,0.0001104426,0.00001576704,0.00003870261,0.9985282,0.00006954342,0.00005652853,0.0007186427],"study_design_scores_gemma":[0.00008325011,0.0005975339,0.01703903,0.00004589137,0.00006567732,0.002157815,0.00009330348,0.0008531614,0.9734978,0.000127382,0.005420995,0.00001810754],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9734026,0.003584904,0.01407723,0.0002958711,0.00009854064,0.0001345225,0.004588502,0.0006835955,0.003134334],"genre_scores_gemma":[0.9556164,0.003197091,0.01374225,0.0002275335,0.00004427665,0.0004290939,0.004228637,0.0003794451,0.02213521],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003539875,"threshold_uncertainty_score":0.01184213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05726247943913454,"score_gpt":0.3102407887739464,"score_spread":0.2529783093348119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}