{"id":"W2300218073","doi":"10.1021/acsami.5b11332","title":"In-Situ-Generated Vasoactive Intestinal Peptide Loaded Microspheres in Mussel-Inspired Polycaprolactone Nanosheets Creating Spatiotemporal Releasing Microenvironment to Promote Wound Healing and Angiogenesis","year":2016,"lang":"en","type":"article","venue":"ACS Applied Materials & Interfaces","topic":"Electrospun Nanofibers in Biomedical Applications","field":"Materials Science","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Ministry of Science and Technology of the People's Republic of China; Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China","keywords":"Materials science; Wound healing; Vasoactive intestinal peptide; Polycaprolactone; Angiogenesis; Nanofiber; Biomedical engineering; Granulation tissue; Membrane; In vivo; Biophysics; Nanotechnology; Chemistry; Composite material; Biochemistry; Medicine; Neuropeptide; Surgery; Biology; Cancer research","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005502847,0.0004483389,0.0006198108,0.0002080863,0.0001800407,0.000235767,0.0004124817,0.0002003314,0.0002448342],"category_scores_gemma":[0.00005166838,0.0003631216,0.00001860949,0.0003843471,0.0002787127,0.0002815402,0.0003541793,0.0001065925,0.0001202973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004619406,"about_ca_system_score_gemma":0.0000748902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006984285,"about_ca_topic_score_gemma":0.0002976437,"domain_scores_codex":[0.9967706,0.0001326051,0.0009711109,0.001024535,0.0003103378,0.0007908707],"domain_scores_gemma":[0.9988412,0.0001923943,0.0003655321,0.0003905396,0.00004585662,0.0001644479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005182285,0.0001465338,0.000248209,0.0000474273,0.00002777019,0.00001279305,0.00100715,0.00000430815,0.9956967,0.00007920809,0.00006043433,0.002151225],"study_design_scores_gemma":[0.0009591449,0.0001659773,0.004162907,0.0003304219,0.00003374378,0.00002468896,0.0001590693,6.89158e-7,0.9932268,0.000448744,0.00005000077,0.0004377983],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964663,0.0001788116,0.0005571001,0.001127928,0.0001757947,0.001230061,0.00006721688,0.00009997296,0.00009677333],"genre_scores_gemma":[0.9723087,0.0000679479,0.02667646,0.0003078333,0.0001025357,0.0003687037,0.00001702463,0.0000652309,0.00008558136],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02611936,"threshold_uncertainty_score":0.9998821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01042233308193255,"score_gpt":0.2418273341332446,"score_spread":0.2314050010513121,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}