{"id":"W2300306696","doi":"10.1021/acs.organomet.5b00967","title":"Transfer Hydrogenation of Nitriles, Olefins, and <i>N</i>-Heterocycles Catalyzed by an <i>N</i>-Heterocyclic Carbene-Supported Half-Sandwich Complex of Ruthenium","year":2016,"lang":"en","type":"article","venue":"Organometallics","topic":"Asymmetric Hydrogenation and Catalysis","field":"Chemistry","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"Regional Municipality of Niagara; Brock University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Carbene; Chemoselectivity; Catalysis; Quinoline; Transfer hydrogenation; Ruthenium; Medicinal chemistry; Hydride; Conjugated system; Acetone; Organic chemistry; Benzonitrile; Metal","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001877266,0.0003522442,0.0006721831,0.000313278,0.00008176725,0.00002377816,0.0004018059,0.0002447064,0.001310812],"category_scores_gemma":[0.00005999255,0.0002842323,0.0002002608,0.0006083412,0.0002534464,0.0003910176,0.00007248175,0.0001030236,0.00001212064],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005851406,"about_ca_system_score_gemma":0.00004135035,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001407448,"about_ca_topic_score_gemma":0.00006913533,"domain_scores_codex":[0.9976336,0.00005551114,0.0008791278,0.0005324856,0.0005526746,0.0003466017],"domain_scores_gemma":[0.9985198,0.0001228863,0.0002986349,0.0006273745,0.000182452,0.0002487864],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004924379,0.0002960352,0.00231318,0.0001280449,0.0002528663,0.000001880248,0.0001922515,0.000002716033,0.9880371,0.0002244129,0.00005208697,0.00845015],"study_design_scores_gemma":[0.001841636,0.00004167128,0.0003089407,0.00002757681,0.0002454331,0.00001622251,0.0001435815,0.0001960766,0.9919075,0.00009390728,0.004826692,0.0003507188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950381,0.0005604916,0.001676277,0.0001291165,0.00002846093,0.0001247414,0.0007786986,0.00008314407,0.001581],"genre_scores_gemma":[0.9979129,0.0004534768,0.000159336,0.00005792175,0.0000379446,0.00001694751,0.0009925241,0.00006876166,0.0003002007],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00809943,"threshold_uncertainty_score":0.999961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01391377096131563,"score_gpt":0.2232400887338934,"score_spread":0.2093263177725778,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}