{"id":"W2300419386","doi":"10.1093/eurheartj/ehw046","title":"Percent reduction in LDL cholesterol following high-intensity statin therapy: potential implications for guidelines and for the prescription of emerging lipid-lowering agents","year":2016,"lang":"en","type":"article","venue":"European Heart Journal","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":219,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; AstraZeneca","keywords":"Medicine; Statin; Medical prescription; Ldl cholesterol; Cholesterol; Reduction (mathematics); Internal medicine; Pharmacology; Cardiology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001745529,0.00008534231,0.0002012834,0.00007124436,0.0002130306,0.00002692214,0.00005029891,0.00001918103,0.000004685673],"category_scores_gemma":[0.0001522439,0.00004927902,0.0002136874,0.00004809865,0.00002108236,0.0001124354,0.00002216121,0.00009412316,5.529611e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004850339,"about_ca_system_score_gemma":0.00003700344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003551001,"about_ca_topic_score_gemma":0.000002826374,"domain_scores_codex":[0.9990473,0.0000921668,0.0003782454,0.0001522414,0.0001513685,0.0001786962],"domain_scores_gemma":[0.9993684,0.00002385586,0.0001090544,0.0001912819,0.0002314942,0.00007592764],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0007542632,0.00009686703,0.01363031,0.0001043896,0.0003294922,0.000004600749,0.001020847,0.000194222,0.3795079,0.00001924277,0.005230454,0.5991074],"study_design_scores_gemma":[0.004563576,0.0003861841,0.9717988,0.0004722715,0.0001084618,0.0005070938,0.0003330165,0.0002491625,0.002527476,0.00006207816,0.01889659,0.00009531056],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9122657,0.0006180728,0.07433384,0.01134504,0.0006399346,0.0007726619,0.000007450494,0.00001125544,0.00000601357],"genre_scores_gemma":[0.9941866,0.001031775,0.003080464,0.0002616404,0.001325275,0.00001829632,0.000002902555,0.00002700223,0.00006609406],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9581684,"threshold_uncertainty_score":0.200954,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09460294380599962,"score_gpt":0.3573059544128658,"score_spread":0.2627030106068662,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}