{"id":"W2300591931","doi":"10.1096/fj.201500116","title":"ECL1i, d(LGTFLKC), a novel, small peptide that specifically inhibits CCL2‐dependent migration","year":2016,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Université Pierre et Marie Curie; Institut National de la Santé et de la Recherche Médicale","keywords":"CCR2; Allosteric regulation; Chemistry; Pharmacology; Chemotaxis; Chemokine receptor; In vivo; Chemokine; Experimental autoimmune encephalomyelitis; Biochemistry; Receptor; Cell biology; Biology; Inflammation; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007804208,0.0001861003,0.000255678,0.00009105566,0.0002109945,0.00008496597,0.0001750823,0.00008700933,0.001072071],"category_scores_gemma":[0.0001343188,0.000087803,0.0002057264,0.0001011349,0.00005847242,0.0001126494,0.00004979097,0.0004140437,0.0001435608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001733012,"about_ca_system_score_gemma":0.0001345041,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001752102,"about_ca_topic_score_gemma":0.00004421151,"domain_scores_codex":[0.9985291,0.00005832047,0.000369312,0.0001920804,0.0005113722,0.0003398175],"domain_scores_gemma":[0.9989843,0.0001473523,0.0002103572,0.0002538793,0.0001512624,0.0002528985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002372066,0.000123905,0.009430896,0.000009382321,0.00006863503,0.00004969817,0.0003326724,0.000005309131,0.9793607,0.0001062941,0.002938719,0.007336576],"study_design_scores_gemma":[0.003132454,0.0002604096,0.004989158,0.0005157314,0.0001266401,0.003050332,0.000373114,0.00007192263,0.977134,0.000242954,0.009903044,0.0002002245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9758557,0.0002481174,0.01229313,0.009467002,0.0003645603,0.0001782492,0.000008019593,0.00003610133,0.001549124],"genre_scores_gemma":[0.9914334,0.0003628141,0.0008146774,0.0004876571,0.001732432,0.000003461024,0.000004005817,0.0000308104,0.005130768],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01557768,"threshold_uncertainty_score":0.9998411,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04355589613686046,"score_gpt":0.2488066827158756,"score_spread":0.2052507865790151,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}