{"id":"W2300680829","doi":"10.1128/aac.02240-15","title":"Effect of High-Dose Antimicrobials on Biofilm Growth of Achromobacter Species Isolated from Cystic Fibrosis Patients","year":2015,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Infections and bacterial resistance","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Tobramycin; Colistin; Microbiology; Aztreonam; Amikacin; Levofloxacin; Cystic fibrosis; Biofilm; Achromobacter; Antibiotics; Biology; Antimicrobial; Aminoglycoside; Bacteria; Gentamicin; Pseudomonas; Antibiotic resistance; Imipenem","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002821338,0.0002658027,0.0005433909,0.0003166062,0.0002198727,0.0003286798,0.000131477,0.0003313826,0.0007692684],"category_scores_gemma":[0.001316351,0.0001842269,0.0002263871,0.0002013372,0.0001996237,0.000170829,0.000324942,0.0004122545,0.0001848404],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001838401,"about_ca_system_score_gemma":0.0001643214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001167437,"about_ca_topic_score_gemma":0.001767952,"domain_scores_codex":[0.9996058,0.0001342309,0.00004694347,0.00005416341,0.0000976528,0.00006120995],"domain_scores_gemma":[0.9994376,0.0001783334,0.00009930017,0.00002830697,0.0001092223,0.0001472297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01213035,0.001562631,0.110982,0.0004678712,0.0002479008,0.001548156,0.0009510117,0.000722765,0.8223092,0.00006938577,0.0005672147,0.04844153],"study_design_scores_gemma":[0.0003126231,0.05092936,0.6360897,0.0001166474,0.000348381,0.004125296,0.00148496,0.001670308,0.3011044,0.0001165402,0.003622315,0.00007944548],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986083,0.0009671653,0.00005290514,0.0000410127,0.00000741788,0.00000745726,0.00004842156,0.00000393036,0.0002633982],"genre_scores_gemma":[0.9990401,0.0003710609,0.0002880045,0.00004442672,0.000007777944,0.00000602022,0.00008273182,0.000001901512,0.0001580662],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001167437,"threshold_uncertainty_score":0.002573431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005769298148707341,"score_gpt":0.2200678347039724,"score_spread":0.214298536555265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}