{"id":"W2300796136","doi":"10.1681/asn.v122252","title":"Abnormal Glomerular Basement Membrane Laminins in Murine, Canine, and Human Alport Syndrome","year":2001,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Alport syndrome; Laminin; Type IV collagen; Basement membrane; Glomerular basement membrane; Immunofluorescence; Biology; Pathology; Glomerulonephritis; Molecular biology; Endocrinology; Chemistry; Kidney; Immunology; Cell biology; Extracellular matrix; Antibody; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006419963,0.0001338847,0.0006520163,0.0001258615,0.00005652841,0.00000498195,0.0002395078,0.00005813191,0.0001584675],"category_scores_gemma":[0.00003463671,0.00009408881,0.0002864623,0.0004700184,0.0007639441,0.00004688129,0.0001598455,0.0005249167,0.000001578261],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001101755,"about_ca_system_score_gemma":0.0001709976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008246137,"about_ca_topic_score_gemma":0.00008230499,"domain_scores_codex":[0.9983137,0.0001363408,0.000572392,0.0001473369,0.000510043,0.0003202515],"domain_scores_gemma":[0.9987599,0.00008733799,0.00058393,0.0002691439,0.0001454341,0.0001542325],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005888346,0.0005416308,0.4152705,0.000104489,0.0004453566,0.001089561,0.000523655,0.00006600544,0.566985,0.00002657587,0.01258102,0.001777423],"study_design_scores_gemma":[0.001991486,0.0021354,0.9712494,0.00005155885,0.00008609741,0.006045324,0.0007902954,0.0001357336,0.001374873,0.00002124682,0.01603627,0.00008229858],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990351,0.0001981409,0.00002494625,0.008983914,0.00002691926,0.0001568909,0.000002044759,0.000003984502,0.0002521549],"genre_scores_gemma":[0.9925114,0.001021326,0.001429113,0.004477601,0.00008327362,0.00000232961,0.000001313951,0.0000176116,0.0004560607],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5656101,"threshold_uncertainty_score":0.383683,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01738222663491463,"score_gpt":0.3010961652670779,"score_spread":0.2837139386321633,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}