{"id":"W2301066148","doi":"10.1007/978-3-319-23603-2_6","title":"Functional Implications of Domain Organization Within Prokaryotic Rhomboid Proteases","year":2015,"lang":"en","type":"review","venue":"Advances in experimental medicine and biology","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Innovates - Health Solutions","keywords":"Rhomboid; Proteases; Transmembrane protein; Cleave; Transmembrane domain; Serine; Protease; Serine protease; Chemistry; Lipid bilayer; Biochemistry; Functional diversity; Enzyme; Biology; Cell biology; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000621833,0.0006255953,0.0009936544,0.001134735,0.0001791215,0.001092963,0.0006685895,0.0008922533,0.0008483244],"category_scores_gemma":[0.000626579,0.0002985989,0.0002736914,0.001392137,0.0008093189,0.001249639,0.0007273611,0.001421447,0.0006376532],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006423999,"about_ca_system_score_gemma":0.0009154187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005043703,"about_ca_topic_score_gemma":0.0008141421,"domain_scores_codex":[0.9998507,0.00001965764,0.0000211617,0.0000364095,0.00005118234,0.00002081441],"domain_scores_gemma":[0.9998054,0.00008864662,0.00003948949,0.000006901038,0.0000386655,0.00002103707],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001211049,0.00003370198,0.0002666884,0.01144021,0.00007229249,0.0003475077,0.00007809111,0.0007005181,0.01299648,0.009086095,0.01062366,0.9542338],"study_design_scores_gemma":[0.00002882344,0.00009962175,0.001538852,0.001560744,0.0001554329,0.00193337,0.000086903,0.0003119735,0.004504175,0.005556721,0.9841881,0.00003532688],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003478379,0.9985423,0.0002908151,0.0002284683,0.0001031138,0.000002526045,0.00001272025,0.000004817266,0.0004674011],"genre_scores_gemma":[0.001888425,0.9970324,0.0003326665,0.0001459488,0.0001432294,0.000004405439,0.00003209789,0.0000012346,0.0004196594],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001134735,"threshold_uncertainty_score":0.004660964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04232774967702847,"score_gpt":0.3781121376003609,"score_spread":0.3357843879233324,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}