{"id":"W2301373251","doi":"10.1002/anie.201681161","title":"Frontispiece: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere","year":2016,"lang":"en","type":"paratext","venue":"Angewandte Chemie International Edition","topic":"Chemistry and Chemical Engineering","field":"Environmental Science","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Drug Research and Development","funders":"","keywords":"Bioisostere; Cubane; Benzene; Benzene derivatives; Chemistry; Molecule; Organic chemistry; Chemical synthesis; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001016525,0.0004178663,0.0003061708,0.00004887317,0.00008456074,0.00009161634,0.0005939571,0.0004502748,0.09166586],"category_scores_gemma":[0.0001724549,0.0003835899,0.0002013308,0.0001046246,0.00010986,0.0003456839,0.0003077002,0.0003665486,0.01407115],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006506837,"about_ca_system_score_gemma":0.00002466952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006702885,"about_ca_topic_score_gemma":0.000003378714,"domain_scores_codex":[0.9978763,0.00001021991,0.000404296,0.0006627294,0.0006810838,0.000365325],"domain_scores_gemma":[0.9990816,0.000124014,0.0002731579,0.0003150493,0.00004013765,0.0001660438],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002130164,0.00004569362,0.00002129339,0.00005150572,0.00007198748,0.00001202663,0.00003182164,0.00004662485,0.5061572,0.000004322269,0.4912173,0.002318962],"study_design_scores_gemma":[0.000286248,0.00001158293,0.00001588182,0.0002993114,0.0000245003,0.00002932483,0.00001265374,0.0000170141,0.6596937,0.0002061916,0.3390795,0.0003241606],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.02090837,0.0003384551,0.002865154,0.001754958,0.005741556,0.00025271,0.001107757,0.0001552017,0.9668759],"genre_scores_gemma":[0.4737097,0.001426896,0.001542811,0.001116375,0.01489895,0.0003324822,0.006071278,0.0002305142,0.500671],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.4662048,"threshold_uncertainty_score":0.9998616,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01023744073888447,"score_gpt":0.2298577238996164,"score_spread":0.2196202831607319,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}