{"id":"W2301452727","doi":"10.1038/srep23043","title":"Metabolic Reprogramming by Hexosamine Biosynthetic and Golgi N-Glycan Branching Pathways","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":131,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; Canada Research Chairs; Canadian Liver Foundation; Vanderbilt University","keywords":"Glycan; Biochemistry; Glycosyltransferase; Lipid metabolism; Metabolism; Glutamine; Biology; Uridine diphosphate; Biosynthesis; Golgi apparatus; Chemistry; Cell; Amino acid; Enzyme; Glycoprotein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008712732,0.0003682289,0.0001618387,0.0001522284,0.00009992965,0.0004103833,0.0001262437,0.0002181859,0.0008442919],"category_scores_gemma":[0.00007088118,0.0001273307,0.0003462455,0.0001286768,0.0001651753,0.0002654549,0.0003041151,0.0004173671,0.0001918887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002889517,"about_ca_system_score_gemma":0.0002210403,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006740881,"about_ca_topic_score_gemma":0.001141923,"domain_scores_codex":[0.9999024,0.00001376446,0.000006683529,0.00002977069,0.00002324094,0.00002418072],"domain_scores_gemma":[0.9999402,0.000002970827,0.00001870276,0.00000752255,0.0000107963,0.00001980039],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001330311,0.000007599042,0.000503097,0.00003175196,0.000005965028,0.00005334912,0.00001293934,0.00005417602,0.9968983,0.0002038398,0.00002730183,0.002068703],"study_design_scores_gemma":[0.00002818139,0.0004298497,0.05353596,0.00004015732,0.00006296858,0.0005396727,0.0001471672,0.001364076,0.9348532,0.0006188174,0.008354,0.00002601207],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889487,0.002663056,0.00435743,0.0001224356,0.0000482932,0.00002345847,0.0005411224,0.0001145104,0.003180908],"genre_scores_gemma":[0.9885374,0.002539342,0.0038261,0.0001222433,0.0000136337,0.000031159,0.0005718852,0.00003347371,0.004324703],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008442919,"threshold_uncertainty_score":0.002824485,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0130931103958361,"score_gpt":0.230628958565735,"score_spread":0.2175358481698989,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}