{"id":"W2301452727","doi":"10.1038/srep23043","title":"Metabolic Reprogramming by Hexosamine Biosynthetic and Golgi N-Glycan Branching Pathways","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":131,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; Canada Research Chairs; Canadian Liver Foundation; Vanderbilt University","keywords":"Glycan; Biochemistry; Glycosyltransferase; Lipid metabolism; Metabolism; Glutamine; Biology; Uridine diphosphate; Biosynthesis; Golgi apparatus; Chemistry; Cell; Amino acid; Enzyme; Glycoprotein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001177337,0.0001555206,0.0003310316,0.0001596422,0.0002154394,0.0001268197,0.00004141298,0.0000604885,0.0002092964],"category_scores_gemma":[0.0009595077,0.00009565068,0.00008422004,0.0003166336,0.0003265742,0.0001449466,0.00004769415,0.00006631751,0.00003443682],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002783214,"about_ca_system_score_gemma":0.00008334326,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002840887,"about_ca_topic_score_gemma":0.000002526206,"domain_scores_codex":[0.9980387,0.00003437647,0.0004194089,0.0007632163,0.0003933642,0.0003509423],"domain_scores_gemma":[0.9985796,0.00008205447,0.0001841934,0.0007700096,0.00009498157,0.0002892241],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001442043,0.00007561494,0.02994905,0.00003387533,0.00003548329,0.000143416,0.0001373555,4.783139e-8,0.8174869,0.0001190717,0.008504408,0.1435004],"study_design_scores_gemma":[0.0007947757,0.0000932861,0.005522149,0.0002831731,0.0001485541,0.000913492,0.0001095352,0.00002836123,0.4363897,0.00195513,0.5535079,0.0002539991],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900432,0.002431454,0.0003301644,0.0007243797,0.002323198,0.000269883,0.000004403785,0.0001674433,0.003705837],"genre_scores_gemma":[0.9896024,0.00003733386,0.0007090227,0.0001066785,0.00008745898,0.0000198059,0.0000203216,0.0000197404,0.009397186],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5450035,"threshold_uncertainty_score":0.3900522,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0130931103958361,"score_gpt":0.230628958565735,"score_spread":0.2175358481698989,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}