{"id":"W2301752124","doi":"10.1093/annonc/mdu344.44","title":"A Phase Ii Study (Nct01883323) Evaluating the Infusion of Autologous Tumor-Infiltrating Lymphocytes (Til) and Low-Dose Interleukin-2 (Il-2) Therapy Following Non-Myeloablative Lymphodepletion Using Cyclophosphamide and Fludarabine in Patients with Metastatic Melanoma","year":2014,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Fludarabine; Cyclophosphamide; Oncology; Chemotherapy; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001316719,0.0013975,0.002128247,0.0003801463,0.0004380245,0.0009296723,0.0007958122,0.0017338,0.005810774],"category_scores_gemma":[0.0008645403,0.0005821533,0.001260401,0.0004776553,0.001093023,0.0007624875,0.0003360555,0.003981183,0.001386839],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006983268,"about_ca_system_score_gemma":0.001928258,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008697461,"about_ca_topic_score_gemma":0.002285651,"domain_scores_codex":[0.999644,0.000185519,0.00001682315,0.00005990851,0.00002180683,0.00007195154],"domain_scores_gemma":[0.9993431,0.0001417527,0.0001048533,0.000062035,0.00003109004,0.0003172031],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8710724,0.05080019,0.003499523,0.000517651,0.0006537635,0.0001635701,0.0002018635,0.001103191,0.0232563,0.0002601424,0.002500568,0.04597086],"study_design_scores_gemma":[0.7126205,0.2797657,0.003928441,0.00002073472,0.0002308945,0.0001075336,0.00003572818,0.0004242538,0.001183482,0.000125399,0.001544442,0.00001298982],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879214,0.001205249,0.0008663039,0.0006539744,0.0002899669,0.004798827,0.001601626,0.0001176199,0.002545155],"genre_scores_gemma":[0.979336,0.001474456,0.002753493,0.001602293,0.0004440951,0.007497759,0.003152503,0.00004905,0.00369044],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005810774,"threshold_uncertainty_score":0.01943898,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06449802489123993,"score_gpt":0.4067606033523453,"score_spread":0.3422625784611053,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}