{"id":"W2302523537","doi":"10.1016/j.exer.2016.03.013","title":"Biological effect of LOXL1 coding variants associated with pseudoexfoliation syndrome","year":2016,"lang":"en","type":"article","venue":"Experimental Eye Research","topic":"Microbial metabolism and enzyme function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Medical Research Council; National Health and Medical Research Council; Heart and Stroke Foundation of Canada","keywords":"Single-nucleotide polymorphism; Pseudoexfoliation syndrome; Biology; Gene; Genetics; Extracellular matrix; Immunoprecipitation; Extracellular; Genotype; Glaucoma","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007704201,0.0001036246,0.0001550111,0.00006527267,0.00008433839,0.000009241648,0.0001278099,0.0001363894,0.0001213457],"category_scores_gemma":[0.0002842142,0.00005879882,0.00004495161,0.0001463462,0.0001587878,0.000007173401,0.0001092334,0.00006994402,0.00002874525],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004042075,"about_ca_system_score_gemma":0.00003002151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002052433,"about_ca_topic_score_gemma":0.000001687841,"domain_scores_codex":[0.9986885,0.000389228,0.0001336178,0.0002761302,0.0002285482,0.0002840182],"domain_scores_gemma":[0.99956,0.00006367516,0.00004806122,0.0001857406,0.0000779488,0.00006459172],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004689624,0.00008662295,0.00404079,0.000005551929,0.00004105088,0.000004792164,0.00002112216,5.342584e-7,0.9941195,0.00007685403,0.0007583858,0.0003758766],"study_design_scores_gemma":[0.001204642,0.002478257,0.01218452,0.00005392454,0.000003877135,0.00000925513,0.00001854434,0.000003328831,0.9835366,0.000009168017,0.00040809,0.00008978073],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985415,0.0003646466,0.0002096709,0.0000349334,0.00009737237,0.0002246929,0.00002931856,0.00001028013,0.000487583],"genre_scores_gemma":[0.9992006,0.00006564685,0.00003542262,0.000009361028,0.00007317503,0.00003437641,0.00004725487,0.00001386249,0.000520279],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01058284,"threshold_uncertainty_score":0.2397746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0331597527589669,"score_gpt":0.3402980185367928,"score_spread":0.3071382657778259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}