{"id":"W2302648836","doi":"10.1007/978-1-4939-3578-9_3","title":"Study Design for Sequencing Studies","year":2016,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Gene expression and cancer classification","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre","funders":"","keywords":"DNA sequencing; Computational biology; Computer science; Genomics; Biology; Genome; DNA; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03708906,0.002714966,0.003157272,0.002618573,0.002589223,0.002643495,0.002439082,0.003044348,0.1005059],"category_scores_gemma":[0.05025493,0.001989893,0.001395263,0.001961785,0.00245516,0.001534852,0.002564865,0.002893868,0.02076727],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001445515,"about_ca_system_score_gemma":0.01092846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001257615,"about_ca_topic_score_gemma":0.002693188,"domain_scores_codex":[0.972181,0.01651512,0.002833123,0.005401741,0.002061778,0.001007283],"domain_scores_gemma":[0.9604403,0.01608191,0.003522845,0.009488878,0.007563051,0.002902892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.1273232,0.005698397,0.02583529,0.02706409,0.002684761,0.001963543,0.004379303,0.007651362,0.05063041,0.06021766,0.1365466,0.5500054],"study_design_scores_gemma":[0.05535315,0.02781971,0.02559783,0.006484945,0.002611042,0.0009720429,0.0009619917,0.01432342,0.02120836,0.05896825,0.7853792,0.0003200036],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"protocol","genre_gemma":"methods","genre_scores_codex":[0.02853625,0.003130009,0.4253806,0.001923506,0.003310532,0.487346,0.02515745,0.00218241,0.02303339],"genre_scores_gemma":[0.03566723,0.0007379048,0.1694358,0.004312681,0.0006690681,0.7755338,0.004008169,0.0005061469,0.009129117],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.1005059,"threshold_uncertainty_score":0.3362256,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1504118345931071,"score_gpt":0.4825481119805861,"score_spread":0.332136277387479,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}