{"id":"W2304069640","doi":"10.1001/jamapsychiatry.2016.0129","title":"Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women","year":2016,"lang":"en","type":"article","venue":"JAMA Psychiatry","topic":"Schizophrenia research and treatment","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Division of Cancer Epidemiology and Genetics, National Cancer Institute; Lawrence Berkeley National Laboratory; David Geffen School of Medicine, University of California, Los Angeles; Russian Academy of Sciences; Economic and Social Research Council; Uppsala Universitet; University of Galway; Tartu Ülikool; Medical Research Council; Roy J. and Lucille A. Carver College of Medicine, University of Iowa; McLean Hospital; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai; Stanley Center for Psychiatric Research, Broad Institute; Universität Wien; Department of Psychiatry, Columbia University; Queen's University; Johns Hopkins Bloomberg School of Public Health; University of North Carolina at Chapel Hill; Pfizer; University of California, Los Angeles; National Institutes of Health; H. Lundbeck A/S; Rheinische Friedrich-Wilhelms-Universität Bonn; National Health and Medical Research Council; Pomorski Uniwersytet Medyczny W Szczecinie; King's College London; Centre National de la Recherche Scientifique; National Cancer Institute; Lundbeckfonden; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; National Institute of Mental Health; Eesti Teadusagentuur; Statens Serum Institut; Universiteit van Amsterdam; Queensland Brain Institute; Karolinska Institutet; University of Queensland; Institut National de la Santé et de la Recherche Médicale; Broad Institute; Massachusetts General Hospital; Queen's University Belfast; Washington University in St. Louis; National University of Ireland; Helsingin Yliopisto; U.S. Department of Veterans Affairs; National Institute for Health and Care Research; Aarhus Universitetshospital; Medizinische Universität Wien; University of Colorado Boulder; Aarhus Universitet; Wellcome Trust; University of Southern California; Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles; Pécsi Tudományegyetem; Johns Hopkins University; Virginia Commonwealth University","keywords":"Biobank; Schizophrenia (object-oriented programming); Genome-wide association study; Offspring; Medicine; Demography; Genetics; Psychiatry; Biology; Single-nucleotide polymorphism; Pregnancy; Genotype; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002452769,0.0004579319,0.0005061484,0.001383102,0.0006496165,0.0008474224,0.0008288575,0.0007119468,0.004730796],"category_scores_gemma":[0.01152258,0.0005495808,0.001639777,0.002064987,0.0009218117,0.0003459895,0.001102423,0.0005284421,0.000398901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003522933,"about_ca_system_score_gemma":0.0005622949,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01056189,"about_ca_topic_score_gemma":0.01241008,"domain_scores_codex":[0.9971104,0.001190667,0.0002280232,0.0009334612,0.00034767,0.0001897667],"domain_scores_gemma":[0.9904676,0.004380892,0.002825259,0.001411994,0.0003498959,0.0005643839],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002108947,0.000007555345,0.9969963,0.0000231562,0.0002517696,0.0001646257,0.0001699435,0.00004360146,0.0004966529,0.00008813559,0.00004651937,0.001500904],"study_design_scores_gemma":[0.00001258211,0.00005156771,0.9984438,0.00002641966,0.0002003139,0.0003916845,0.0001382666,0.0001828628,0.0001260787,0.0001798664,0.0002391722,0.000007392704],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962242,0.001265524,0.000653683,0.0002038314,0.00002173053,0.000006050364,0.0005797486,0.00001303535,0.001032279],"genre_scores_gemma":[0.9989426,0.0002933368,0.0002926832,0.00003320847,0.00001458848,0.000006950367,0.0002453924,0.000008998973,0.0001623518],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01056189,"threshold_uncertainty_score":0.0210008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03972290610551468,"score_gpt":0.311565210959175,"score_spread":0.2718423048536603,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). 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