{"id":"W2304398105","doi":"10.1016/j.freeradbiomed.2016.03.017","title":"Impact of aging on mitochondrial function in cardiac and skeletal muscle","year":2016,"lang":"en","type":"review","venue":"Free Radical Biology and Medicine","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre; Christie (Canada); McGill University","funders":"Canadian Institutes of Health Research","keywords":"Skeletal muscle; Mitochondrion; Mitochondrial permeability transition pore; Reactive oxygen species; Cell biology; Cardiac muscle; Biology; Mitochondrial DNA; Myocyte; Internal medicine; Endocrinology; Apoptosis; Biochemistry; Programmed cell death; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005747607,0.0007561798,0.001171881,0.001111106,0.0001932401,0.0008288323,0.0006839585,0.0009204557,0.001875864],"category_scores_gemma":[0.0007057015,0.0001746307,0.0003153503,0.001278582,0.0004551432,0.0009962654,0.0007882719,0.0011719,0.0008382446],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004003301,"about_ca_system_score_gemma":0.0008469647,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008440756,"about_ca_topic_score_gemma":0.001854029,"domain_scores_codex":[0.999882,0.00001479108,0.00001911386,0.00002952636,0.00004081958,0.00001386589],"domain_scores_gemma":[0.9997194,0.0001105108,0.00004976485,0.00001000535,0.00008478052,0.00002547205],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009656184,0.00003861625,0.0003232466,0.01183982,0.00008968935,0.0001785,0.00004037988,0.000274095,0.002570829,0.002160429,0.01520162,0.9671863],"study_design_scores_gemma":[0.00002745892,0.0001559981,0.002919561,0.004653808,0.000371888,0.00161574,0.000118218,0.0001614595,0.001679898,0.004895116,0.9833634,0.00003759964],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001280522,0.9991432,0.0001017429,0.000174055,0.0001435058,0.000001483868,0.00001631909,0.00000351403,0.0002881468],"genre_scores_gemma":[0.0007879341,0.9984921,0.0001199301,0.0001163162,0.000177002,0.000002592246,0.00002174708,7.470154e-7,0.0002815693],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001875864,"threshold_uncertainty_score":0.006275415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01845294096897213,"score_gpt":0.3270583169275738,"score_spread":0.3086053759586017,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}