{"id":"W2304898873","doi":"10.1038/labinvest.2016.46","title":"Inhibition of endotoxin-induced airway epithelial cell injury by a novel family of pyrrol derivates","year":2016,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Michael's Hospital","funders":"Instituto de Salud Carlos III","keywords":"Downregulation and upregulation; ARDS; Lipopolysaccharide; Apoptosis; Inflammation; Pharmacology; A549 cell; Tumor necrosis factor alpha; Immunology; Medicine; Chemistry; Lung; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001279181,0.0003312474,0.0002212284,0.0002001462,0.0001692758,0.0001837534,0.0002716123,0.0002263955,0.001595279],"category_scores_gemma":[0.0000976895,0.00009177799,0.00022136,0.0001095126,0.0002039893,0.0002680447,0.0001775568,0.0004073725,0.0003048239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001743539,"about_ca_system_score_gemma":0.0001580377,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000240722,"about_ca_topic_score_gemma":0.0003502836,"domain_scores_codex":[0.9999502,0.000007988487,0.000004082806,0.00001141429,0.000008967098,0.00001740654],"domain_scores_gemma":[0.9999558,0.000007650451,0.00001303797,0.000005670874,0.000005232896,0.00001270847],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009960622,0.0001902785,0.0002376592,0.0001087152,0.00001276577,0.0002781567,0.00004247092,0.000473893,0.9796203,0.0005997799,0.0002434755,0.01719649],"study_design_scores_gemma":[0.0002122359,0.00518496,0.003654083,0.00001720224,0.00003653304,0.0009145061,0.00002962726,0.001389595,0.9749005,0.000173549,0.01346791,0.0000192882],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842781,0.004977915,0.005405675,0.0002309858,0.00006493184,0.00007977709,0.0003244122,0.0001774841,0.004460707],"genre_scores_gemma":[0.9878371,0.003436479,0.00422911,0.0001388519,0.00003895391,0.00005480922,0.0003768759,0.00001803018,0.003869735],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001595279,"threshold_uncertainty_score":0.005336761,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00909097882989065,"score_gpt":0.2048285837576111,"score_spread":0.1957376049277204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}